Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress

J Jing, Y He, Y Liu, J Tang, L Wang, G Jia, G Liu… - Journal of Animal …, 2023 - Springer
Background The skeletal muscle of pigs is vulnerable to oxidative damage, resulting in
growth retardation. Selenoproteins are important components of antioxidant systems for …

[HTML][HTML] Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and …

J Jing, J Wang, X Xiang, S Yin, J Tang, L Wang, G Jia… - Animal Nutrition, 2024 - Elsevier
In the present study, the chronic heat stress (CHS) broiler model was developed to
investigate the potential protection mechanism of organic selenium (selenomethionine …

[HTML][HTML] Multi-Omics Profiling Reveals Se Deficiency–Induced Redox Imbalance, Metabolic Reprogramming, and Inflammation in Pig Muscle

K Zhang, S Li, Q Zhao, J Li, Y Han, Y Qin, J Zhang… - The Journal of …, 2022 - Elsevier
Background Nutritional muscle dystrophy is associated with selenium (Se) deficiency;
however, the underlying mechanism remains unclear. Objectives This study aimed to …

Hydroxy selenomethionine improves meat quality through optimal skeletal metabolism and functions of selenoproteins of pigs under chronic heat stress

Y Liu, S Yin, J Tang, Y Liu, G Jia, G Liu, G Tian, X Chen… - Antioxidants, 2021 - mdpi.com
Chronic heat stress (CHS) induces metabolic changes in skeletal muscle from growth to
maintenance that jeopardizes growth performance, carcass traits, and meat quality of pigs …

Selenoproteins protect against avian nutritional muscular dystrophy by metabolizing peroxides and regulating redox/apoptotic signaling

JQ Huang, FZ Ren, YY Jiang, C Xiao, XG Lei - Free Radical Biology and …, 2015 - Elsevier
Nutritional muscular dystrophy (NMD) of chicks is induced by dietary selenium (Se)/vitamin
E (Vit. E) deficiencies and may be associated with oxidative cell damage. To reveal the …

Low-Se diet increased mitochondrial ROS to suppress myoblasts proliferation and promote apoptosis in broilers via miR-365-3p/SelT signaling axis

H Wu, T Xu, N Yang, J Zhang, S Xu - Journal of Agricultural and …, 2023 - ACS Publications
microRNA (miRNA) controls the post-transcriptional translation of mRNA to affect the
expression of many genes participating in functional interaction pathways. Selenoproteins …

Selenium deficiency-induced oxidative stress causes myocardial injury in calves by activating inflammation, apoptosis, and necroptosis

L Lei, J Mu, Y Zheng, Y Liu - Antioxidants, 2023 - mdpi.com
Selenium (Se) is essential for human and animal health, but there have been few studies on
the mechanisms of injury in dairy cows with Se deficiency. This study aimed to evaluate the …

Selenogenome and AMPK signal insight into the protective effect of dietary selenium on chronic heat stress-induced hepatic metabolic disorder in growing pigs

Y Liu, J Tang, Y He, G Jia, G Liu, G Tian… - Journal of Animal …, 2021 - Springer
Background Chronic heat stress (CHS) disrupts hepatic metabolic homeostasis and
jeopardizes product quality of pigs. Selenium (Se) may regulate the metabolic state through …

Cellular antioxidant mechanism of selenium-enriched yeast diets in the protection of meat quality of heat-stressed hens

B Liu, YL Xiong, J Jiang, D Yu, G Lin - Food Bioscience, 2021 - Elsevier
The effects and mechanisms of dietary selenium-enriched yeast (SeY, at Se 0, 0.25, and
0.50 mg/kg) on breast meat quality and oxidative stability of heat-stressed laying hens were …

Serine administration improves selenium status, oxidative stress, and mitochondrial function in longissimus dorsi muscle of piglets with intrauterine growth retardation

Y He, Y Liu, P Guan, L He, X Zhou - Biological Trace Element Research, 2023 - Springer
Intrauterine growth retardation (IUGR) causes oxidative stress in the skeletal muscle. Serine
and selenoproteins are involved in anti-oxidative processes; however, whether IUGR affects …