Canine and feline parvoviruses can use human or feline transferrin receptors to bind, enter, and infect cells

JSL Parker, WJ Murphy, D Wang, SJ O'Brien… - Journal of …, 2001 - Am Soc Microbiol
Canine parvovirus (CPV) enters and infects cells by a dynamin-dependent, clathrin-
mediated endocytic pathway, and viral capsids colocalize with transferrin in perinuclear …

Purified feline and canine transferrin receptors reveal complex interactions with the capsids of canine and feline parvoviruses that correspond to their host ranges

LM Palermo, SL Hafenstein, CR Parrish - Journal of virology, 2006 - Am Soc Microbiol
The cell infection processes and host ranges of canine parvovirus (CPV) and feline
panleukopenia virus (FPV) are controlled by their capsid interactions with the transferrin …

Residues in the apical domain of the feline and canine transferrin receptors control host-specific binding and cell infection of canine and feline parvoviruses

LM Palermo, K Hueffer, CR Parrish - Journal of virology, 2003 - Am Soc Microbiol
Canine parvovirus (CPV) and feline panleukopenia virus (FPV) capsids bind to the
transferrin receptors (TfRs) of their hosts and use these receptors to infect cells. The binding …

The natural host range shift and subsequent evolution of canine parvovirus resulted from virus-specific binding to the canine transferrin receptor

K Hueffer, JSL Parker, WS Weichert, RE Geisel… - Journal of …, 2003 - Am Soc Microbiol
Canine parvovirus (CPV) is a host range variant of a feline virus that acquired the ability to
infect dogs through changes in its capsid protein. Canine and feline viruses both use the …

Limited transferrin receptor clustering allows rapid diffusion of canine parvovirus into clathrin endocytic structures

DK Cureton, CE Harbison, E Cocucci… - Journal of …, 2012 - Am Soc Microbiol
Viral pathogens usurp cell surface receptors to access clathrin endocytic structures, yet the
mechanisms of virus incorporation into these structures remain incompletely understood …

Combinations of two capsid regions controlling canine host range determine canine transferrin receptor binding by canine and feline parvoviruses

K Hueffer, L Govindasamy… - Journal of …, 2003 - Am Soc Microbiol
Feline panleukopenia virus (FPV) and its host range variant, canine parvovirus (CPV), can
bind the feline transferrin receptor (TfR), while only CPV binds to the canine TfR. Introducing …

Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs

JT Kaelber, A Demogines, CE Harbison… - PLoS …, 2012 - journals.plos.org
Parvoviruses exploit transferrin receptor type-1 (TfR) for cellular entry in carnivores, and
specific interactions are key to control of host range. We show that several key mutations …

Cellular uptake and infection by canine parvovirus involves rapid dynamin-regulated clathrin-mediated endocytosis, followed by slower intracellular trafficking

JSL Parker, CR Parrish - Journal of virology, 2000 - Am Soc Microbiol
Canine parvovirus (CPV) is a small, nonenveloped virus that is a host range variant of a
virus which infected cats and changes in the capsid protein control the ability of the virus to …

Parvoviral host range and cell entry mechanisms

SF Cotmore, P Tattersall - Advances in virus research, 2007 - Elsevier
Parvoviruses elaborate rugged nonenveloped icosahedral capsids of∼ 260 Å in diameter
that comprise just 60 copies of a common core structural polypeptide. While serving as …

Parvovirus host range, cell tropism and evolution

K Hueffer, CR Parrish - Current opinion in microbiology, 2003 - Elsevier
The past few years have seen major advances in our understanding of the controls of
evolution, host range and cell tropism of parvoviruses. Notable findings have included the …