An overview of repurposed drugs for potential COVID-19 treatment

K Govender, A Chuturgoon - Antibiotics, 2022 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 has placed severe constraints on
healthcare systems around the globe. The SARS-CoV-2 virus has caused upheaval in the …

Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges

V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …

Combating devastating COVID-19 by drug repurposing

AY Pawar - International Journal of Antimicrobial Agents, 2020 - Elsevier
Despite advances in drug discovery, viral infections remain a major challenge for scientists
across the globe. The recent pandemic of COVID-19 (coronavirus disease 2019), caused by …

Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment

NS Taibe, MA Kord, MA Badawy… - Therapeutic …, 2022 - journals.sagepub.com
On 30 January 2020, the World Health Organization (WHO) declared the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic a public health emergency of …

Drugs repurposing for SARS-CoV-2: new insight of COVID-19 druggability

SK Debnath, M Debnath, R Srivastava… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction The ongoing epidemic of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) creates a massive panic worldwide due to the absence of effective …

Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …

Efficacy of repurposed antiviral drugs: lessons from COVID-19

MA Martinez - Drug Discovery Today, 2022 - Elsevier
The clinical, social, and economic impacts of the coronavirus disease 2019 (COVID-19)
pandemic, originated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Challenges for drug repurposing in the COVID-19 pandemic era

J Sultana, S Crisafulli, F Gabbay, E Lynn… - Frontiers in …, 2020 - frontiersin.org
The coronavirus disease (COVID-19) pandemic has affected an estimated 16 million
persons and caused 0.6 million deaths worldwide by September 2020. The pandemic has …

An update on antiviral therapy against SARS-CoV-2: how far have we come?

O Indari, S Jakhmola, E Manivannan… - Frontiers in …, 2021 - frontiersin.org
COVID-19 pandemic has spread worldwide at an exponential rate affecting millions of
people instantaneously. Currently, various drugs are under investigation to treat an …

What Should Be Learned From Repurposed Antivirals Against SARS-CoV-2?

MA Martinez - Frontiers in microbiology, 2022 - frontiersin.org
Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in
2019, more than 270 million infections have been reported, and the death toll from the …