Combating antimicrobial resistance: the silent war

L Bo, H Sun, YD Li, J Zhu, JND Wurpel, H Lin… - Frontiers in …, 2024 - frontiersin.org
Once hailed as miraculous solutions, antibiotics no longer hold that status. The excessive
use of antibiotics across human healthcare, agriculture, and animal husbandry has given …

Tackling antimicrobial resistance by exploring new mechanisms of antibiotic action

CL Matos de Opitz, P Sass - Future Microbiology, 2020 - Taylor & Francis
Antibiotics are undoubtedly one the most influential discoveries in medicine. Following their
introduction in the first half of the last century, the steadily increasing use of antibiotics as …

Novel Approaches to the Treatment of Multidrug-Resistant Bacteria

P Pusparajah, V Letchumanan, BH Goh… - Frontiers in …, 2022 - frontiersin.org
Multidrug-resistant (MDR) organisms constitute a major global health crisis with
antimicrobial resistance (AMR) being among the top ten global public health threats faced …

Novel approaches to the treatment of multidrug-resistant bacteria, Volume II

P Pusparajah, V Letchumanan, BH Goh… - Frontiers in …, 2022 - frontiersin.org
Overall, the articles in this Research Topic highlight a spectrum of research encompassing
the importance of pursuing work to explore new ways of treating multidrug resistant bacteria …

Therapeutic and Unconventional Strategies to Contrast Antimicrobial Resistance: A Literature Review.

A Vitiello, M Sabbatucci, M Boccellino, A Ponzo… - Discovery …, 2023 - europepmc.org
The fast emergence and spread of drug-resistant infectious pathogens and the resulting
increase in associated and attributable deaths is a major health challenge globally. Misuse …

Novel targets and mechanisms in antimicrobial drug discovery

D Tondi - Antibiotics, 2021 - mdpi.com
The spread of infections resistant to available anti-infective drugs is a serious menace to
human health. WHO predicts that in less than 30 years, microbial resistance will become the …

Current approaches to overcome antimicrobial resistance

A Schcolnik-Cabrera - Current Medicinal Chemistry, 2023 - ingentaconnect.com
The phenomenon of antimicrobial resistance (AMR) has surged due to the historical non-
discretional use and the inappropriate prescribing of compounds against microorganisms …

Next-generation approaches needed to tackle antimicrobial resistance for the development of novel therapies against the deadly pathogens

V Bhandari, A Suresh - Frontiers in Pharmacology, 2022 - frontiersin.org
The advent of antimicrobials was a miracle that saved millions of lives across the globe. With
the discovery of penicillin, varieties of other antimicrobials came into play one after another …

New drugs, approaches, and strategies to combat antimicrobial resistance

CK Singh, KK Sodhi, MS Mubarak - Frontiers in Pharmacology, 2023 - frontiersin.org
Multidrug-resistant organisms (MDROs) are microorganisms, mainly bacteria, that have
become resistant to one or more classes of antimicrobial agents and to certain antibiotics …

Targeting antibiotic resistance: from diagnostics to novel antibiotics

J Li, PM Sexton - ACS Pharmacology & Translational Science, 2020 - ACS Publications
1928. Considered as therapeutic “magic-bullets”, antibiotics have revolutionized modern
medicine and made many complicated medical procedures possible. The 1960s and 1970s …