During the formation of ova and sperm, homologous chromosomes get physically attached
through the synaptonemal complex and exchange DNA at crossover sites by a process …

Meiotic chromosomes in human oocytes are packaged differently than in spermatocytes at
the pachytene stage of meiosis I, when crossing-over takes place. Thus the meiosis-specific …

Chromosomes undergoing meiosis are defined by a macromolecular protein assembly
called the synaptonemal complex which holds homologs together and carries out important …

Genetic variability in sexually reproducing organisms results from an exchange of genetic
material between homologous chromosomes. The genetic exchange mechanism is …

The synaptonemal complex (SC) is a mainly proteinaceous structure that is present between
closely paired chromosomes at meiotic prophase. It occurs almost universally in higher …

Chromosome anomalies are extraordinarily common in human gametes, with approximately
21% of oocytes and 9% of spermatozoa abnormal. The types of abnormalities are quite …

During meiotic prophase I, homologous chromosomes synapse and recombine. Both events
are of vital importance for the success of meiosis. When homologous chromosomes …

Meiotic prophase I is the key stage of meiosis and includes several sequential sub-stages
connected with synaptonemal complex (SC), which is the skeletal structure of meiotic …

The synaptonemal complex (SC) is a meiosis-specific nuclear multiprotein complex that is
essential for proper synapsis, recombination and segregation of homologous chromosomes …

The synaptonemal complex is an evolutionarily conserved, supramolecular structure that
holds the homologous chromosomes together during the pachytene stage of the first meiotic …