Sox11‐modified mesenchymal stem cells (MSCs) accelerate bone fracture healing: Sox11 regulates differentiation and migration of MSCs

L Xu, S Huang, Y Hou, Y Liu, M Ni, F Meng… - The FASEB …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are a promising cell resource for tissue engineering. Sry‐
related high‐mobility group box 11 (Sox11) plays critical roles in neural development and …

[HTML][HTML] TNF-α-Induced SOX5 upregulation is involved in the osteogenic differentiation of human bone marrow mesenchymal stem cells through KLF4 signal pathway

L Xu, L Zheng, Z Wang, C Li, S Li, X Xia, P Zhang… - Molecules and cells, 2018 - Elsevier
Postmenopausal osteoporosis (PMOP) is a common systemic skeletal disease
characterized by reduced bone mass and microarchitecture deterioration. Although …

[HTML][HTML] Sox9 modulates proliferation and expression of osteogenic markers of adipose-derived stem cells (ASC)

S Stöckl, C Göttl, J Grifka, S Grässel - Cellular Physiology and …, 2013 - karger.com
Background: Mesenchymal stem cells (MSC) are promising tools for tissue-engineering and
musculoskeletal regeneration. They reside within various tissues, like adipose tissue …

Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation

J Liao, N Hu, N Zhou, L Lin, C Zhao, S Yi, T Fan… - PloS one, 2014 - journals.plos.org
Bone morphogenetic protein 2 (BMP2) is one of the key chondrogenic growth factors
involved in the cartilage regeneration. However, it also exhibits osteogenic abilities and …

Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells

F Yu, F Wu, F Li, X Liao, Y Wang, X Li, C Wang… - Stem Cells, 2020 - academic.oup.com
As a profoundly anabolic regulator of bone, Wnt7b is well acknowledged to enhance
osteoblast activities. Here, we report that bone marrow mesenchymal stem cells (BMSCs) …

Sox4 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cell via activation of long noncoding RNA DANCR

L Zhang, S Chen, N Bao, C Yang, Y Ti, L Zhou… - Journal of molecular …, 2015 - Springer
Mesenchymal stem cells (MSCs) have several features that make them an attractive option
for potentiating cartilage repair. Synovium-derived (SMSCs) have been recently recognized …

[HTML][HTML] Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs)

C Zhao, W Jiang, N Zhou, J Liao, M Yang, N Hu… - Genes & diseases, 2017 - Elsevier
Cartilage injuries caused by arthritis or trauma pose formidable challenges for effective
clinical management due to the limited intrinsic proliferative capability of chondrocytes …

Sox9 modulates cell survival and adipogenic differentiation of multipotent adult rat mesenchymal stem cells

S Stöckl, RJ Bauer, AK Bosserhoff… - Journal of cell …, 2013 - journals.biologists.com
Sox9 is a key transcription factor in early chondrogenesis with distinct roles in differentiation
processes and during embryonic development. Here, we report that Sox9 modulates cell …

In Vitro Osteogenic Potential of Human Mesenchymal Stem Cells Is Predicted by Runx2/Sox9 Ratio

C Loebel, EM Czekanska, M Bruderer… - … Engineering Part A, 2015 - liebertpub.com
Introduction: Runx2 is one of the most studied transcription factors expressed in
mesenchymal stem cells (MSCs) upon their commitment toward an osteogenic …

[HTML][HTML] Homeobox B7 promotes the osteogenic differentiation potential of mesenchymal stem cells by activating RUNX2 and transcript of BSP

RT Gao, LP Zhan, C Meng, N Zhang… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are a reliable cell source for tissue regeneration. However,
the molecular mechanisms underlying the directed differentiation of MSCs remain unclear; …