Evaluation of the relationship between IL-6 gene single nucleotide polymorphisms and the severity of COVID-19 in an Iranian population

S Falahi, MH Zamanian, P Feizollahi, A Rezaiemanesh… - Cytokine, 2022 - Elsevier
Background Emerged coronavirus disease 2019 (COVID-19) is a pandemic caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). Disease severity is …

Role of SNPs of IL6 gene in the incidence and progression of COVID19 patients in Wasit province

AA Mahmood, DA Gheni, MI Ibrahim… - Journal of …, 2022 - pnrjournal.com
Background: SARS-coronavirus 2 is the causative of the COVID-19 pandemic.(SARS-COV-
2). There is a correlation between illness severity and cytokines of proinflammation such as …

Influence of IL-6 rs1800795 and IL-8 rs2227306 polymorphisms on COVID-19 outcome

AA Ghazy - The Journal of Infection in Developing Countries, 2023 - jidc.org
Introduction: Severe coronavirus disease 2019 (COVID-19) is mainly precipitated by an
uncontrolled inflammatory response and cytokine storm. Pro-inflammatory cytokines such as …

Genetic Polymorphism of Interleukin-6 in Asymptomatic and ICU-Admitted COVID-19 Patients in Sulaymaniyah Province, Kurdistan Region of Iraq

PMA Rashid, GF Salih - Genetic Testing and Molecular Biomarkers, 2024 - liebertpub.com
Background: The global pandemic of Coronavirus Disease 2019 (COVID-19) has resulted in
significant fatality rates. Clinical outcomes for affected individuals range from being …

Role of Interleukin-6 and Tumor Necrosis Factor-Alpha Genes Polymorphisms in COVID-19 Progression

EM Ghoneim, A Abd El Raouf Khalil… - Egyptian Journal of …, 2024 - ejmm.journals.ekb.eg
Background: IL6 and tumor necrosis factor-ɑ (TNF-ɑ) are important cytokines that determine
the host defense mechanism, that play a pivotal role in COVID-19 progression. Objectives …

IL-6 Gene (174G/C) Single Nucleotide Polymorphism as an Indicator of COVID-19 Severity in Egyptian Patients

BS Kasem, RS Sharshar… - … of Advances in …, 2024 - publish.sub7journal.com
IL-6 Gene (174G/C) Single Nucleotide Polymorphism as an Indicator of COVID-19 Severity
in Egyptian Patients Bsant Safwat Kasem Ragia S. Sharshar Wesam Salah Ibrahim Hesham …

Association of Interleukin-6 (rs1800795) and Interleukin-10 (rs1800896) Genetic Polymorphisms with the Outcome of COVID-19 Infection: A Single Center Study

M El-Bendary, M Naemattalah, H Elalfy… - Viral …, 2024 - liebertpub.com
The corona virus disease-2019 (COVID-19) pandemic has affected most of the world with
varying degrees of morbidity and mortality. The presence of genetic polymorphisms may be …

[HTML][HTML] Association between interleukin-10 gene polymorphisms (rs1800871, rs1800872, and rs1800896) and severity of infection in different SARS-CoV-2 variants

SJA Abbood, E Anvari, A Fateh - Human Genomics, 2023 - Springer
Background Polymorphisms in the interleukin-10 (IL10) gene have been linked to the
severity of the patients infected with the viral infections. This study aimed to assess if the …

[PDF][PDF] Polymorphism in promotor region of IL6 gene as a predictor for severity in COVID-19 patients

SA Aladawy, LA Adel, SAA Salam, RH Raafat… - Egypt J …, 2022 - academia.edu
SARS-CoV-2 is the causative agent of coronavirus disease started in 2019 (COVID-19). IL-6
gene is located on chromosome 7. A considerable number of polymorphisms was identified …

[HTML][HTML] Study on the association between interleukin-6 receptor Asp358Ala (rs2228145) single nucleotide polymorphism, with the severity of clinical symptoms in …

A Rashidi, S Ghaffarpour, MS Zamani… - Daneshvar …, 2022 - daneshvarmed.shahed.ac.ir
Background and Objective: Increasing of interleukin-6 (IL-6) in Covid-19 patients has been
reported in various studies. Genetic variants of the IL-6 receptor are involved in the …