Deferiprone: a forty-year-old multi-targeting drug with possible activity against COVID-19 and diseases of similar symptomatology

GJ Kontoghiorghes - International Journal of Molecular Sciences, 2022 - mdpi.com
The need for preparing new strategies for the design of emergency drug therapies against
COVID-19 and similar diseases in the future is rather urgent, considering the high rate of …

Deferoxamine has the potential to improve the COVID-19-related inflammatory response in diabetic patients

M Zeinivand, M Sharifi, G Hassanshahi… - International journal of …, 2023 - Springer
The clinical state of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
been considered a pandemic disease (COVID-19) that is rapidly spreading worldwide …

Pulmonary delivery of fenretinide: a possible adjuvant treatment in COVID-19

I Orienti, GA Gentilomi, G Farruggia - International journal of molecular …, 2020 - mdpi.com
At present, there is no vaccine or effective standard treatment for severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) infection (or coronavirus disease-19 (COVID-19)) …

[HTML][HTML] Teriflunomide: A possible effective drug for the comprehensive treatment of COVID-19

AM Rabie - Current research in pharmacology and drug discovery, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has undoubtedly become a
global crisis. Consequently, discovery and identification of new or known potential drug …

Conventional and Unconventional Approaches for Innovative Drug Treatments in COVID-19: Looking Outside of Plato's Cave

GJ Kontoghiorghes, A Kolnagou, S Fetta… - International Journal of …, 2021 - mdpi.com
Thousands of drugs and nutraceuticals along with their combinations can be used to select
candidate therapeutics for targeting the transmission, proliferation and the fatal or severe …

Reply: iron chelation may harm patients with COVID-19

A Abobaker - European Journal of Clinical Pharmacology, 2021 - Springer
Dear Editor A strikingly high level of ferritin has been reported in patients with the novel
coronavirus disease 2019 (COVID-19)[1]. One of the possible explanations of this …

[HTML][HTML] Therapeutic potential of induced iron depletion using iron chelators in Covid-19

PP Naseef, M Elayadeth-Meethal, KTM Salim… - Saudi Journal of …, 2022 - Elsevier
Ferritin, which includes twenty-four light and heavy chains in varying proportions in different
tissues, is primarily responsible for maintaining the body's iron metabolism. Its normal value …

Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences

E Campione, C Lanna, T Cosio, L Rosa… - Frontiers in …, 2021 - frontiersin.org
Lactoferrin (Lf) is a cationic glycoprotein synthetized by exocrine glands and is present in all
human secretions. It is also secreted by neutrophils in infection and inflammation sites. This …

Can iron chelation as an adjunct treatment of COVID-19 improve the clinical outcome?

A Abobaker - European Journal of Clinical Pharmacology, 2020 - Springer
Dear Editor; A recent bioinformatic study showed that one of the important pathogenic effects
of coronavirus disease 2019 (COVID-19) is through the direct damage of haemoglobin …

Ferritin as a biomarker of infection in COVID-19 non-hospitalized patients

AA Yameny - Journal of Bioscience and Applied Research, 2021 - jbaar.journals.ekb.eg
Background: Serum ferritin is an iron storage protein with a primary role of regulating cellular
oxygen metabolism, Ferritin has emerged as a key in the immune system, and its role as an …