Changes in DNA methylation from pre-to post-adolescence are associated with pubertal exposures
Background Adolescence is a period characterized by major biological development, which
may be associated with changes in DNA methylation (DNA-M). However, it is unknown to …
may be associated with changes in DNA methylation (DNA-M). However, it is unknown to …
Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence
DNA methylation (DNAm) is known to play a pivotal role in childhood health and
development, but a comprehensive characterization of genome-wide DNAm trajectories …
development, but a comprehensive characterization of genome-wide DNAm trajectories …
Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study
S Chen, H Refaey, N Mukherjee… - Human …, 2020 - academic.oup.com
STUDY QUESTION Is the age of onset of pubertal markers related to subsequent changes in
DNA methylation (DNAm)? SUMMARY ANSWER We identified 273 cytosine-phosphate …
DNA methylation (DNAm)? SUMMARY ANSWER We identified 273 cytosine-phosphate …
Predictors and consequences of global DNA methylation in cord blood and at three years
JB Herbstman, S Wang, FP Perera, SA Lederman… - PloS one, 2013 - journals.plos.org
DNA methylation changes have been implicated in many common chronic diseases leading
to the hypothesis that environmental and age-related DNA methylation changes within …
to the hypothesis that environmental and age-related DNA methylation changes within …
DNA methylation sites in early adulthood characterised by pubertal timing and development: a twin study
Background Puberty is a highly heritable and variable trait, with environmental factors
having a role in its eventual timing and development. Early and late pubertal onset are both …
having a role in its eventual timing and development. Early and late pubertal onset are both …
Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune …
EE Thompson, J Nicodemus-Johnson, KW Kim… - Clinical …, 2018 - Springer
Background The changes that occur during puberty have been implicated in susceptibility to
a wide range of diseases later in life, many of which are characterized by sex-specific …
a wide range of diseases later in life, many of which are characterized by sex-specific …
Lymphoblastoid cell lines reveal associations of adult DNA methylation with childhood and current adversity that are distinct from whole blood associations
M Suderman, JJ Pappas, N Borghol… - International Journal …, 2015 - academic.oup.com
Background: Some cohort studies bank lymphoblastoid cell lines (LCLs) as a renewable
source of participant DNA. However, although LCL DNA has proved valuable for genetic …
source of participant DNA. However, although LCL DNA has proved valuable for genetic …
Intra-individual changes in DNA methylation not mediated by cell-type composition are correlated with aging during childhood
K Gervin, BK Andreassen, HS Hjorthaug… - Clinical …, 2016 - Springer
Background Several studies have reported age-associated changes in DNA methylation in
the first few years of life and in adult populations, but the extent of such changes during …
the first few years of life and in adult populations, but the extent of such changes during …
Gender-affirming hormone therapy induces specific DNA methylation changes in blood
Background DNA methylation is an epigenetic mark that is influenced by underlying genetic
profile, environment, and ageing. In addition to X-linked DNA methylation, sex-specific …
profile, environment, and ageing. In addition to X-linked DNA methylation, sex-specific …
Longitudinal analysis of DNA methylation associated with birth weight and gestational age
Gestational age (GA) and birth weight have been implicated in the determination of long-
term health. It has been hypothesized that changes in DNA methylation may mediate these …
term health. It has been hypothesized that changes in DNA methylation may mediate these …