[HTML][HTML] Sex differences in brain aging among adults with family history of Alzheimer's disease and APOE4 genetic risk

S Subramaniapillai, S Rajagopal, J Snytte, AR Otto… - NeuroImage: Clinical, 2021 - Elsevier
Emerging evidence suggests that Alzheimer's Disease (AD) risk factors may differentially
contribute to disease trajectory in women than men. Determining the effect of AD risk factors …

Sex‐and age‐specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort

S Subramaniapillai, S Suri, C Barth… - Human brain …, 2022 - Wiley Online Library
Cardiometabolic risk (CMR) factors are associated with accelerated brain aging and
increased risk for sex‐dimorphic illnesses such as Alzheimer's disease (AD). Yet, it is …

Alzheimer's disease genetic risk, cognition, and brain aging in midlife

WD Brenowitz, M Fornage, LJ Launer… - Annals of …, 2023 - Wiley Online Library
We examined associations of an Alzheimer's disease (AD) Genetic Risk Score (AD‐GRS)
and midlife cognitive and neuroimaging outcomes in 1,252 middle‐aged participants (311 …

Sex differences in the association between AD biomarkers and cognitive decline

MEI Koran, M Wagener, TJ Hohman… - Brain imaging and …, 2017 - Springer
Women are disproportionately affected by Alzheimer's disease (AD) in terms of both disease
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …

Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts

RF Buckley, EC Mormino, RE Amariglio… - Alzheimer's & …, 2018 - Elsevier
Introduction Our objective was to investigate the effect of sex on cognitive decline within the
context of amyloid β (Aβ) burden and apolipoprotein E genotype. Methods We analyzed sex …

The Effect of the APOE Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease

LC Löwe, C Gaser, K Franke… - PloS one, 2016 - journals.plos.org
In our aging society, diseases in the elderly come more and more into focus. An important
issue in research is Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with …

Are sex differences in cognitive impairment reflected in epigenetic age acceleration metrics?

AM Inkster, P Duarte-Guterman, AY Albert… - Neurobiology of …, 2022 - Elsevier
Sex differences are well-established in Alzheimer's disease (AD) frequency and
pathogenesis, but are not mechanistically understood. Accelerated epigenetic age has been …

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints

E Cavedo, PA Chiesa, M Houot, MT Ferretti… - Alzheimer's & …, 2018 - Elsevier
Introduction Observational multimodal neuroimaging studies indicate sex differences in
Alzheimer's disease pathophysiological markers. Methods Positron emission tomography …

Sex differences in cognitive decline in subjects with high likelihood of mild cognitive impairment due to Alzheimer's disease

D Sohn, K Shpanskaya, JE Lucas, JR Petrella… - Scientific reports, 2018 - nature.com
Sex differences in Alzheimer's disease (AD) biology and progression are not yet fully
characterized. The goal of this study is to examine the effect of sex on cognitive progression …

Effects of APOE haplotypes and measures of cardiovascular risk over gender-dependent cognitive and functional changes in one year in Alzheimer's disease

FF de Oliveira, FV Pereira, GAK Pivi… - International Journal …, 2018 - Taylor & Francis
Background: Illiteracy, high cerebrovascular risk and copies of APOE-ϵ4 are risk factors for
Alzheimer's disease dementia (AD). We aimed to investigate the impacts of gender …