Our understanding of the roles played by zinc in the physiological and pathological
functioning of the brain is rapidly expanding. The increased availability of genetically …

The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology.
The recent development of powerful tools, including zinc-sensitive fluorescent probes …

Zinc is a life‐sustaining trace element, serving structural, catalytic, and regulatory roles in
cellular biology. It is required for normal mammalian brain development and physiology …

▪ Abstract Zinc is an essential catalytic or structural element of many proteins, and a
signaling messenger that is released by neural activity at many central excitatory synapses …

Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

Zinc is an essential trace element, whose importance to the function of the central nervous
system (CNS) is increasingly being appreciated. Alterations in zinc dyshomeostasis has …

The trace metal zinc is a biofactor that plays essential roles in the central nervous system
across the lifespan from early neonatal brain development through the maintenance of brain …

In addition to its familiar role as a component of metalloproteins, zinc is also sequestered in
the presynaptic vesicles of a specialized type of neurons calledzinc-containing'neurons …

Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

Zinc is one of the most abundant transition metals in the brain. A substantial fraction (10–
15%) of brain zinc is located inside presynaptic vesicles of certain glutamatergic terminals in …