The role of IL-6 in coronavirus, especially in COVID-19

X Wang, G Tang, Y Liu, L Zhang, B Chen… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects both people and
animals and may cause significant respiratory problems, including lung illness: Corona …

The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics

M Abbasifard, H Khorramdelazad - Life sciences, 2020 - Elsevier
Abstract Interleukin-6 (IL-6), known as an inflammatory cytokine, can be involved in many
innate and adaptive immune responses. The role of IL-6 in the pathogenesis of the novel …

Relationship between IL-6 and COVID-19: to be considered during treatment

HS Vatansever, E Becer - Future Virology, 2020 - Taylor & Francis
The detection and control of pro-inflammatory response is crucial in the early stages of viral
infection. Coronavirus disease 2019 (COVID-19) is an emerging viral disease of global …

[HTML][HTML] Rethinking interleukin-6 blockade for treatment of COVID-19

S Scherger, A Henao-Martínez, C Franco-Paredes… - Medical hypotheses, 2020 - Elsevier
Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with effects in immune regulation,
inflammation, and infection. The use of drugs that inhibit IL-6 biological activity has been …

Interleukin-1 in COVID-19 Infection: Immunopathogenesis and Possible Therapeutic Perspective

A Mardi, S Meidaninikjeh, S Nikfarjam… - Viral …, 2021 - liebertpub.com
The newfound coronavirus disease 2019 (COVID-19), initiated by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is an international public health concern …

[HTML][HTML] Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications

J Majidpoor, K Mortezaee - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Interleukin-6 (IL-6) is a multi-tasking cytokine that represents high activity in patients
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and cancer. High …

An important call: Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications

LJ Shih, CC Yang, MT Liao, KC Lu, WC Hu, CP Lin - Virulence, 2023 - Taylor & Francis
The global coronavirus disease 2019 (COVID-19) pandemic has a detrimental impact on
public health. COVID-19 usually manifests as pneumonia, which can progress into acute …

The role of IL-6 and IL-6 blockade in COVID-19

N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …

The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19

S Makaremi, A Asgarzadeh, H Kianfar… - Inflammation …, 2022 - Springer
A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …

Interleukin-6 perpetrator of the COVID-19 cytokine storm

J Shekhawat, K Gauba, S Gupta, P Purohit… - Indian Journal of Clinical …, 2021 - Springer
COVID-19 has emerged as a global pandemic. It is mainly manifested as pneumonia which
may deteriorate into severe respiratory failure. The major hallmark of the disease is the …