Environmental pollution stands as one of the most critical challenges affecting human
health, with an estimated mortality rate linked to pollution-induced non-communicable …

Oxidative stress (OS) plays an important role in the pathogenesis of a variety of autoimmune
diseases (ADs) and many environmental agents participate in this process. Environmental …

There is substantial evidence that environmental triggers in combination with genetic and
stochastic factors play an important role in spontaneous autoimmune disease. Although the …

Chemical pollution poses a significant threat to human health, with detrimental effects on
various physiological systems, including the respiratory, cardiovascular, mental, and …

The incidence of autoimmunity is growing rapidly worldwide. Many epidemiological studies
have found environmental factors, such as toxic chemicals (persistent organic pollutants …

Autoimmune diseases (ADs) are a broad spectrum of disorders featured by the body's
immune responses being directed against its own tissues, resulting in prolonged …

The influence of environmental factors on the development of autoimmune disease is being
broadly investigated to better understand the multifactorial nature of autoimmune …

Pathogenesis of many autoinflammatory and autoimmune diseases is largely driven by
inappropriate or inadequate immune responses toward environmental challenges. Most of …

Autoimmune diseases comprise a very heterogeneous group of disorders characterized by
disruptive immune responses against self-antigens, chronic morbidity and increased …

IFN-γ has been found to be robustly important to disease pathogenesis in both idiopathic
and induced models of murine lupus. In transgenic mice, over production of IFN-γ in the skin …