Linked dimensions of psychopathology and connectivity in functional brain networks

CH Xia, Z Ma, R Ciric, S Gu, RF Betzel… - Nature …, 2018 - nature.com
Neurobiological abnormalities associated with psychiatric disorders do not map well to
existing diagnostic categories. High co-morbidity suggests dimensional circuit-level …

Connectome-wide network analysis of youth with Psychosis-Spectrum symptoms

TD Satterthwaite, SN Vandekar, DH Wolf… - Molecular …, 2015 - nature.com
Adults with psychotic disorders have dysconnectivity in critical brain networks, including the
default mode (DM) and the cingulo-opercular (CO) networks. However, it is unknown …

Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness

D Wang, M Li, M Wang, F Schoeppe, J Ren… - Molecular …, 2020 - nature.com
Neuroimaging studies of psychotic disorders have demonstrated abnormalities in structural
and functional connectivity involving widespread brain networks. However, these group …

Functional connectomics of affective and psychotic pathology

JT Baker, DG Dillon, LM Patrick… - Proceedings of the …, 2019 - National Acad Sciences
Converging evidence indicates that groups of patients with nominally distinct psychiatric
diagnoses are not separated by sharp or discontinuous neurobiological boundaries. In …

Shared and specific patterns of structural brain connectivity across affective and psychotic disorders

J Repple, M Gruber, M Mauritz, SC de Lange… - Biological …, 2023 - Elsevier
Background Altered brain structural connectivity has been implicated in the pathophysiology
of psychiatric disorders including schizophrenia (SZ), bipolar disorder (BD), and major …

A connectome-wide functional signature of transdiagnostic risk for mental illness

ML Elliott, A Romer, AR Knodt, AR Hariri - Biological psychiatry, 2018 - Elsevier
Background High rates of comorbidity, shared risk, and overlapping therapeutic
mechanisms have led psychopathology research toward transdiagnostic dimensional …

The human cortex possesses a reconfigurable dynamic network architecture that is disrupted in psychosis

JM Reinen, OY Chén, RM Hutchison, BTT Yeo… - Nature …, 2018 - nature.com
Higher-order cognition emerges through the flexible interactions of large-scale brain
networks, an aspect of temporal coordination that may be impaired in psychosis. Here, we …

Associations between resting-state functional connectivity and a hierarchical dimensional structure of psychopathology in middle childhood

NR Karcher, G Michelini, R Kotov, DM Barch - … Cognitive Neuroscience and …, 2021 - Elsevier
Background Previous research from the Adolescent Brain Cognitive Development (ABCD)
Study delineated and validated a hierarchical 5-factor structure with a general …

How can studies of resting-state functional connectivity help us understand psychosis as a disorder of brain development?

TD Satterthwaite, JT Baker - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Psychosis is increasingly understood as a disorder of neurodevelopment.•
Resting state fMRI powerfully describes brain development and psychosis.•Here we review …

[HTML][HTML] Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study

J Chen, A Tam, V Kebets, C Orban, LQR Ooi… - Nature …, 2022 - nature.com
How individual differences in brain network organization track behavioral variability is a
fundamental question in systems neuroscience. Recent work suggests that resting-state and …