A revolution in cellular measurement technology is under way: For the first time, we have the
ability to monitor global gene regulation in thousands of individual cells in a single …

High‐throughput‐omics techniques have revolutionised biology, allowing for thorough and
unbiased characterisation of the molecular states of biological systems. However, cellular …

The cumulative activity of all of the body's cells, with their myriad interactions, life histories,
and environmental experiences, gives rise to a condition that is distinctly human and specific …

Individual cells of the same phenotype are commonly viewed as identical functional units of
a tissue or organ. However, the deep sequencing of DNA and RNA from single cells …

Single-cell analysis is a rapidly evolving approach to characterize genome-scale molecular
information at the individual cell level. Development of single-cell technologies and …

Single-cell multi-omics has recently emerged as a powerful technology by which different
layers of genomic output—and hence cell identity and function—can be recorded …

Single-cell genomics has now made it possible to create a comprehensive atlas of human
cells. At the same time, it has reopened definitions of a cell's identity and of the ways in …

Every Cell Is Special: Genome-wide Studies Add a New Dimension to Single-Cell Biology: Cell
Skip to Main Content Advertisement Cell This journal offers authors two options (open access …

Traditionally, gene expression measurements were performed on “bulk” samples containing
populations of thousands of cells. Recent advances in genomic technology have made it …

Three of the most fundamental questions in biology are how individual cells differentiate to
form tissues, how tissues function in a coordinated and flexible fashion and which gene …