Rapid metagenomic sequencing for diagnosis and antimicrobial sensitivity prediction of canine bacterial infections
Antimicrobial resistance is a major threat to human and animal health. There is an urgent
need to ensure that antimicrobials are used appropriately to limit the emergence and impact …
need to ensure that antimicrobials are used appropriately to limit the emergence and impact …
Comprehensive pathogen identification, antibiotic resistance, and virulence genes prediction directly from simulated blood samples and positive blood cultures by …
M Zhou, Y Wu, T Kudinha, P Jia, L Wang, Y Xu… - Frontiers in …, 2021 - frontiersin.org
Bloodstream infection is a major cause of morbidity and mortality worldwide. We explored
whether MinION nanopore sequencing could accelerate diagnosis, resistance, and …
whether MinION nanopore sequencing could accelerate diagnosis, resistance, and …
Comparison of 16S and whole genome dog microbiomes using machine learning
Background Recent advances in sequencing technologies have driven studies identifying
the microbiome as a key regulator of overall health and disease in the host. Both 16S …
the microbiome as a key regulator of overall health and disease in the host. Both 16S …
Genomics accurately predicts antimicrobial resistance in Staphylococcus pseudintermedius collected as part of Vet-LIRN resistance monitoring
GH Tyson, O Ceric, J Guag, S Nemser… - Veterinary …, 2021 - Elsevier
Whole-genome sequencing (WGS) has changed our understanding of bacterial pathogens,
aiding outbreak investigations and advancing our knowledge of their genetic features …
aiding outbreak investigations and advancing our knowledge of their genetic features …
Rapid detection of bacterial pathogens and antimicrobial resistance genes in clinical urine samples with urinary tract infection by metagenomic nanopore sequencing
L Zhang, W Huang, S Zhang, Q Li, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Urinary tract infections (UTIs) are among the most common acquired bacterial infections in
humans. The current gold standard method for identification of uropathogens in clinical …
humans. The current gold standard method for identification of uropathogens in clinical …
Shallow metagenomics with Nanopore sequencing in canine fecal microbiota improved bacterial taxonomy and identified an uncultured CrAssphage
A Cuscó, A Salas, C Torre, O Francino - bioRxiv, 2019 - biorxiv.org
Long-read metagenomics–using single-molecule sequencers–has the potential to assembly
entire genomes, even from complex metagenomics datasets. Using long-read …
entire genomes, even from complex metagenomics datasets. Using long-read …
Evaluating the potential of third generation metagenomic sequencing for the detection of BRD pathogens and genetic determinants of antimicrobial resistance in …
CN Freeman, EK Herman, J Abi Younes… - BMC veterinary …, 2022 - Springer
Background Bovine respiratory disease (BRD) is an important cause of morbidity and
mortality and is responsible for most of the injectable antimicrobial use in the feedlot …
mortality and is responsible for most of the injectable antimicrobial use in the feedlot …
Non-Targeted RNA Sequencing: Towards the Development of Universal Clinical Diagnosis Methods for Human and Veterinary Infectious Diseases
Simple Summary With advances in NGS technology, the high ratio of throughput/cost per
base has allowed research laboratories to develop diagnostic protocols that can detect …
base has allowed research laboratories to develop diagnostic protocols that can detect …
Enhancing the one health initiative by using whole genome sequencing to monitor antimicrobial resistance of animal pathogens: Vet-LIRN collaborative project with …
O Ceric, GH Tyson, LB Goodman, PK Mitchell… - BMC veterinary …, 2019 - Springer
Background Antimicrobial resistance (AMR) of bacterial pathogens is an emerging public
health threat. This threat extends to pets as it also compromises our ability to treat their …
health threat. This threat extends to pets as it also compromises our ability to treat their …
[HTML][HTML] The canine skin and ear microbiome: A comprehensive survey of pathogens implicated in canine skin and ear infections using a novel next-generation …
S Tang, A Prem, J Tjokrosurjo, M Sary, MA Van Bel… - Veterinary …, 2020 - Elsevier
This study analyzed the complex bacterial and fungal microbiota of healthy and clinically
affected canine ear and skin samples. A total of 589 canine samples were included: 257 ear …
affected canine ear and skin samples. A total of 589 canine samples were included: 257 ear …