Background Advanced therapies using adult mesenchymal stromal cells (MSCs) for
neurodegenerative diseases are not effectively translated into the clinic. The cross talk …

Stem cell transplantation is a potential curative treatment for degenerative diseases of the
retina. Among cell injection sites, the subretinal space (SRS) is particularly advantageous as …

Mesenchymal stromal cell (MSC) therapy to treat neurodegenerative diseases has not been
as successful as expected in some preclinical studies. Because preclinical research is so …

We examined myelin formation by oligodendrocytes co-transplanted with
immunosuppressive mesenchymal stem cells (MSCs). Oligodendrocyte precursor cells …

Background Glaucoma is a blinding degenerative neuropathy in which the death of retinal
ganglion cells (RGCs) causes progressive loss of visual field and eventually vision …

Incurable neuroretinal degeneration diseases cause severe vision loss and blindness in
millions of patients worldwide. In previous studies, we demonstrated that transplanting …

Background and Objectives: Irreversible visual impairment is mainly caused by retinal
degenerative diseases such as age-related macular degeneration and retinitis pigmentosa …

The remarkable plasticity of marrow stromal cells (MSCs) after transplantation to models of
neurological disease and injury has been described. In this report, we investigated the …

There is an increasing effort toward generating replacement cells for neuronal application
due to the nonregenerative nature of these tissues. While much progress has been made …

The transplantation of neuronal cells and tissues represents a promising approach for the
treatment of incurable neurodegenerative diseases. Indeed, it has been reported recently …