[HTML][HTML] In silico drug repurposing in COVID-19: A network-based analysis
The SARS-CoV-2 pandemic is a worldwide public health emergency. Despite the beginning
of a vaccination campaign, the search for new drugs to appropriately treat COVID-19 …
of a vaccination campaign, the search for new drugs to appropriately treat COVID-19 …
[HTML][HTML] Network bioinformatics analysis provides insight into drug repurposing for COVID-19
X Li, J Yu, Z Zhang, J Ren, AE Peluffo, W Zhang… - Medicine in Drug …, 2021 - Elsevier
The COVID-19 disease caused by the SARS-CoV-2 virus is a health crisis worldwide. While
developing novel drugs and vaccines is long, repurposing existing drugs against COVID-19 …
developing novel drugs and vaccines is long, repurposing existing drugs against COVID-19 …
SAveRUNNER: A network-based algorithm for drug repurposing and its application to COVID-19
The novelty of new human coronavirus COVID-19/SARS-CoV-2 and the lack of effective
drugs and vaccines gave rise to a wide variety of strategies employed to fight this worldwide …
drugs and vaccines gave rise to a wide variety of strategies employed to fight this worldwide …
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus
(SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead …
(SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead …
[HTML][HTML] Integrating heterogeneous data to facilitate COVID-19 drug repurposing
LP Santamaría, MD Uzquiano, EU Carro… - Drug Discovery …, 2022 - Elsevier
In the COVID-19 pandemic, drug repositioning has presented itself as an alternative to the
time-consuming process of generating new drugs. This review describes a drug repurposing …
time-consuming process of generating new drugs. This review describes a drug repurposing …
Drug repurposing for COVID-19 treatment by integrating network pharmacology and transcriptomics
Since coronavirus disease 2019 (COVID-19) is a serious new worldwide public health crisis
with significant morbidity and mortality, effective therapeutic treatments are urgently needed …
with significant morbidity and mortality, effective therapeutic treatments are urgently needed …
A connectivity map-based drug repurposing study and integrative analysis of transcriptomic profiling of SARS-CoV-2 infection
SZ Mousavi, M Rahmanian, A Sami - Infection, Genetics and Evolution, 2020 - Elsevier
Aims The recent outbreak of COVID-19 has become a global health concern. There are
currently no effective treatment strategies and vaccines for the treatment or prevention of this …
currently no effective treatment strategies and vaccines for the treatment or prevention of this …
Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach
T Loganathan, S Ramachandran, P Shankaran… - PeerJ, 2020 - peerj.com
Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been declared a pandemic by the World Health …
syndrome coronavirus 2 (SARS-CoV-2) has been declared a pandemic by the World Health …
In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential …
A Lopez-Cortes, P Guevara-Ramirez… - Frontiers in …, 2021 - frontiersin.org
Background: There is pressing urgency to identify therapeutic targets and drugs that allow
treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune …
treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune …
[HTML][HTML] Drug repurposing for COVID-19 using graph neural network with genetic, mechanistic, and epidemiological validation
Amid the pandemic of 2019 novel coronavirus disease (COVID-19) infected by SARS-CoV-
2, a vast amount of drug research for prevention and treatment has been quickly conducted …
2, a vast amount of drug research for prevention and treatment has been quickly conducted …