Mechanisms of action of ozone therapy in emerging viral diseases: immunomodulatory effects and therapeutic advantages with reference to SARS-CoV-2

A Cenci, I Macchia, V La Sorsa, C Sbarigia… - Frontiers in …, 2022 - frontiersin.org
Medical oxygen-ozone (O2-O3) is a successful therapeutic approach accounting on the
assessed beneficial action of ozone in the range 30–45 μg/ml (expanded range 10–80 …

The Mito-Hormetic mechanisms of ozone in the clearance of SARS-CoV2 and in the COVID-19 therapy

S Chirumbolo, A Varesi, M Franzini, L Valdenassi… - Biomedicines, 2022 - mdpi.com
An increasing body of evidence in the literature is reporting the feasibility of using medical
ozone as a possible alternative and adjuvant treatment for COVID-19 patients, significantly …

Ozone (O3) and SARS-CoV-2: physiological bases and their therapeutic possibilities according to COVID-19 evolutionary stage

ME Fernández-Cuadros, MJ Albaladejo-Florín… - SN Comprehensive …, 2020 - Springer
To date, there is no definitive treatment for the new SARS-CoV-2 pandemic. Three
evolutionary stages in SARS-CoV-2 infection are recognized (early infection, pulmonary …

Insights on the mechanisms of action of ozone in the medical therapy against COVID-19

S Chirumbolo, L Valdenassi, V Simonetti… - International …, 2021 - Elsevier
An increasing amount of reports in the literature is showing that medical ozone (O 3) is used,
with encouraging results, in treating COVID-19 patients, optimizing pain and symptoms …

Ozone therapy in COVID-19: A narrative review

F Cattel, S Giordano, C Bertiond, T Lupia, S Corcione… - Virus research, 2021 - Elsevier
The main objective of this narrative review is to describe the available evidence on the
possible antiviral activity of ozone in patients with COVID-19 and its therapeutic applicability …

Ozone therapy for the treatment of COVID-19 pneumonia: A scoping review

M Izadi, L Cegolon, M Javanbakht, A Sarafzadeh… - International …, 2021 - Elsevier
Severe forms of COVID-19 can evolve into pneumonia, featured by acute respiratory failure
due to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). In viral …

[PDF][PDF] Oxygen-ozone therapy as adjuvant in the current emergency in SARS-COV-2 infection: a clinical study

S Marini, M Maggiorotti, N Dardes… - J Biol Regul Homeost …, 2020 - coren-se.gov.br
In these times of emergency for the pandemic of SARS-CoV-2 many treatment solutions are
under investigation (1). Within this scenario, the oxygenozone mixture, which has shown to …

Oxygen-ozone immunoceutical therapy in COVID-19 outbreak: facts and figures

G Ricevuti, M Franzini, L Valdenassi - Ozone Therapy, 2020 - pagepressjournals.org
The problems related to the approach to the outbreak of COVID-19 in the world require that
all possible effective treatment options be explored. The clinical criterion of the researcher is …

Potential cytoprotective activity of ozone therapy in SARS-CoV-2/COVID-19

G Martínez-Sánchez, A Schwartz, V Di Donna - Antioxidants, 2020 - mdpi.com
(1) Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) disease (COVID-19) in China at the end of 2019 has caused a large global outbreak …

Oxygen-ozone (O2-O3) immunoceutical therapy for patients with COVID-19. Preliminary evidence reported

M Franzini, L Valdenassi, G Ricevuti… - International …, 2020 - Elsevier
Objective This study evaluated the potential efficacy of a novel approach to treat COVID-19
patients, using an oxygen-ozone (O 2-O 3) mixture, via a process called Oxygen-Ozone …