Abstract Background Patients with Parkinson's disease (PD) have consistently demonstrated
brain structure abnormalities, indicating the presence of shared etiological and pathological …

ABSTRACT Background and Objectives Many hereditary movement disorders with complex
phenotypes without a locus symbol prefix for familial PD present as parkinsonism; however …

Background Parkinson's disease (PD) is a neurodegenerative disease with an often
complex component identifiable by genome‐wide association studies. The most recent large …

Background Several reports have identified different patterns of Parkinson's disease
progression in individuals carrying missense variants in GBA or LRRK2 genes. The overall …

Abstract Background The Parkinson's Progression Marker Initiative is an international
multicenter study whose main goal is investigating markers for Parkinson's disease (PD) …

Background Genome‐wide association studies (GWAS) have identified numerous single‐
nucleotide polymorphisms (SNPs) that can modulate the risk of developing Parkinson's …

Background Ethnic‐specific genetic risk assessment framework for Parkinson's disease (PD)
is lacking for the Asian population. Objective We investigated the association of a polygenic …

Background Large‐scale genome‐wide association studies (GWASs) have reported
multiple risk variants for Parkinson's disease (PD). However, little is known about how these …

Background Increasing evidence supports an extensive and complex genetic contribution to
PD. Previous genome‐wide association studies (GWAS) have shed light on the genetic …

Background Recent studies have advanced our understanding of the genetic drivers of
Parkinson's disease (PD). Rare variants in more than 20 genes are considered causal for …