With increasing evidence that microbes colonize tumors, synthetic biology tools are being
leveraged to repurpose bacteria as tumor-specific delivery systems. These engineered …

Synthetic biology aims to apply engineering principles to biology by modulating the behavior
of living organisms. An emerging application of this field is the engineering of bacteria as a …

Bacteria are emerging as living drugs to treat a broad range of disease indications.
However, the inherent advantages of these replicating and immunostimulatory therapies …

Synthetic biology is driving a new era of medicine through the genetic programming of living
cells,. This transformative approach allows for the creation of engineered systems that …

The human body is a natural habitat for a multitude of microorganisms, with bacteria being
the major constituent of the microbiota. These bacteria colonize discrete anatomical …

Recent advances in targeted therapy and immunotherapy have once again raised the hope
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …

Anti-cancer therapy faces major challenges, particularly in terms of specificity of treatment.
The ideal therapy would eradicate tumour cells selectively with minimum side effects on …

Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

Here, we provide a brief overview of the approaches and strategies underlying bacteria-
based cancer immunotherapy (BCiT). We also describe and summarize research in the field …

Recent advances in cancer therapeutics, such as targeted therapy and immunotherapy,
have raised the hope for cures for many cancer types. However, there are still ongoing …