Enalapril attenuated CFA provoked arthritic manifestation by modulating proinflammatory and anti-inflammatory cytokine network

YH Khan, S Qasim, AM Uttra, NH Alotaibi, AS Alanazi… - Life Sciences, 2023 - Elsevier
Enalapril with documented anti-inflammatory potential was evaluated in current investigation
to explore its anti-arthritic efficacy. For anti-arthritic evaluation of enalapril, CFA-instigated …

Appraisal of disease-modifying potential of amlodipine as an anti-arthritic agent: new indication for an old drug

S Qasim, Alamgeer, S Kalsoom, M Shahzad… - …, 2020 - Springer
Amlodipine, a second-generation calcium channel blocker, exhibits documented anti-
inflammatory potential. Thereby, present investigation was accomplished with an aim to …

Appraisal of anti-inflammatory and immunomodulatory potential of ramipril against Freund's adjuvant-provoked arthritic rat model

S Qasim, YH Khan, AM Uttra, NH Alotaibi… - …, 2023 - Springer
Because of evident role of renin–angiotensin system in the etiology of rheumatoid arthritis,
the current study's objective was to assess the anti-arthritic efficacy of ramipril through CFA …

[HTML][HTML] Aliskiren, tadalafil, and cinnamaldehyde alleviate joint destruction biomarkers; MMP-3 and RANKL; in complete Freund's adjuvant arthritis model …

AA Azouz, E Saleh, AA Abo-Saif - Saudi Pharmaceutical Journal, 2020 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease, which is accompanied by
progressive joint damage and disability. The intolerability of conventional antirheumatic …

Appraisal of the antiarthritic potential of prazosin via inhibition of proinflammatory cytokine TNF-α: a key player in rheumatoid arthritis

S Qasim, Alamgeer, M Saleem, NH Alotaibi… - ACS …, 2021 - ACS Publications
Prazosin, a selective α1 adrenergic receptor antagonist, with documented anti-inflammatory
potential, was evaluated for its antiarthritic efficacy by targeting specifically TNF-α. The …

[HTML][HTML] Effect of losartan in complete freund's adjuvant–induced arthritis in rats

OAMA El-Gaphar, AM Abo-Youssef… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by joint
infiltration and bone damage. The aim of the present study was to evaluate the beneficial …

Mechanistic Evaluation of Antiarthritic Effects of Citronellol in CFA-Induced Arthritic Rats

E Dar, A Mobashar, A Shabbir, MN Mushtaq… - ACS …, 2023 - ACS Publications
Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic
inflammation, joint tissue damage, pain, and synovitis. It leads to deformity of joints …

Comparison of diclofenac with apigenin-glycosides rich Clinacanthus nutans extract for amending inflammation and catabolic protease regulations in osteoporotic …

NACA Tantowi, S Mohamed, SF Lau… - Daru Journal of …, 2020 - Springer
Background Osteoporotic-osteoarthritis is an incapacitating musculoskeletal illness of the
aged. Objectives The anti-inflammatory and anti-catabolic actions of Diclofenac were …

[PDF][PDF] Allicin reduces IL-1β-induced inflammatory cytokines via attenuating the NF-κB and MMP3 activation in human osteoarthritis chondrocytes model

W Lin, P Hai-Tao, W Bing, L Yang, F Kai… - Int J Clin Exp …, 2016 - e-century.us
Allicin, a sulphur containing compound isolated from the bulb of Allium sativum, confirm the
various pharmacological activity such as antioxidant and antiinflammatory effects. The …

The roles of synovial hyperplasia, angiogenesis and osteoclastogenesis in the protective effect of apigenin on collagen-induced arthritis

Y Li, B Yang, J Bai, S Xia, M Mao, X Li, N Li… - International …, 2019 - Elsevier
Apigenin (API) is a plant flavone that is known to exert a protective effect in rheumatoid
arthritis (RA), which is a chronic autoimmune disease. However, the molecular mechanism …