Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a
heritability of~ 45–60%. We present genome-wide association studies in British and …

Kidney stone disease (nephrolithiasis) is a common problem that can be associated with
alterations in urinary solute composition including hypercalciuria. Studies suggest that the …

Kidney stone disease is a common disorder in Western countries that is associated with
significant suffering, morbidity, and cost for the healthcare system. Numerous studies have …

Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

Calcium nephrolithiasis is one of the most prevalent uronephrologic disorders in the western
countries. Studies in families and twins evidenced a genetic predisposition to calcium …

Renal stone disease is a frequent condition, causing a huge burden on health care systems
globally. Calcium-based calculi account for around 75% of renal stone disease and the …

Background: Calcium nephrolithiasis is a multifactorial disease with a polygenic milieu.
Association studies identified genetic polymorphisms potentially implicated in the …

Kidney stone disease is a complex disorder with a strong genetic component. We conducted
a genome-wide association study of 28.3 million sequence variants detected through whole …

Kidney stone disease (KSD) is a major clinical problem imposing a large burden for both
healthcare and economy globally. In India, the prevalence of kidney stone disease is rapidly …

With a lifetime incidence of up to 12% in man and 6% in woman, nephrolithiasis is a major
health problem worldwide. Approximately, 80% of kidney stones are composed of calcium …