Enrichment of Elevated Plasma F2t-Isoprostane Levels in Individuals with Autism Who Are Stratified by Presence of Gastrointestinal Dysfunction

P Gorrindo, CJ Lane, EB Lee, BA McLaughlin, P Levitt - PloS one, 2013 - journals.plos.org
Etiology is unknown in the majority of individuals with autism spectrum disorder (ASD). One
strategy to investigate pathogenesis is to stratify this heterogeneous disorder based on a …

Multivariate analysis of plasma metabolites in children with autism spectrum disorder and gastrointestinal symptoms before and after microbiota transfer therapy

JB Adams, T Vargason, DW Kang, R Krajmalnik-Brown… - Processes, 2019 - mdpi.com
Current diagnosis of autism spectrum disorder (ASD) is based on assessment of behavioral
symptoms, although there is strong evidence that ASD affects multiple organ systems …

[HTML][HTML] Plasma and fecal metabolite profiles in autism spectrum disorder

BD Needham, MD Adame, G Serena, DR Rose… - Biological …, 2021 - Elsevier
Background Autism spectrum disorder (ASD) is a neurodevelopmental condition with
hallmark behavioral manifestations including impaired social communication and restricted …

Multivariate Analysis of Metabolomic and Nutritional Profiles among Children with Autism Spectrum Disorder

F Qureshi, JB Adams, T Audhya, J Hahn - Journal of Personalized …, 2022 - mdpi.com
There have been promising results regarding the capability of statistical and machine-
learning techniques to offer insight into unique metabolomic patterns observed in ASD. This …

Plasma metabolomics of autism spectrum disorder and influence of shared components in proband families

MK Chung, MR Smith, Y Lin, DI Walker, D Jones… - …, 2021 - academic.oup.com
Prevalence of autism spectrum disorder (ASD) has been increasing in the United States in
the past decades. The exact mechanisms remain enigmatic, and diagnosis of the disease …

Metabolic profiling in children with autism spectrum disorder with and without mental regression: Preliminary results from a cross-sectional case–control study

OD Rangel-Huerta, A Gómez-Fernández… - Metabolomics, 2019 - Springer
Introduction It is challenging to establish the mechanisms involved in the variety of well-
defined clinical phenotypes in autism spectrum disorder (ASD) and the pathways involved in …

Increased excretion of a lipid peroxidation biomarker in autism

X Ming, TP Stein, M Brimacombe, WG Johnson… - … and essential fatty acids, 2005 - Elsevier
It is thought that autism could result from an interaction between genetic and environmental
factors with oxidative stress as a potential mechanism linking the two. One genetic factor …

Altered autonomic functions and gut microbiome in individuals with autism spectrum disorder (ASD): implications for assisting ASD screening and diagnosis

X Kong, J Liu, K Liu, M Koh, R Tian, C Hobbie… - Journal of Autism and …, 2021 - Springer
Autism spectrum disorder (ASD) is a complex neurological and developmental disorder, and
a growing body of literature suggests the presence of autonomic nervous system (ANS) …

Urinary untargeted metabolic profile differentiates children with autism from their unaffected siblings

AM Timperio, F Gevi, F Cucinotta, A Ricciardello… - Metabolites, 2022 - mdpi.com
Autism Spectrum Disorder (ASD) encompasses a clinical spectrum of neurodevelopmental
conditions that display significant heterogeneity in etiology, symptomatology, and severity …

Classification of autism spectrum disorder from blood metabolites: Robustness to the presence of co-occurring conditions

T Vargason, E Roth, G Grivas, J Ferina, RE Frye… - Research in Autism …, 2020 - Elsevier
Background Previous studies have found plasma measurements of metabolites from the
folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathways to be …