In COVID-19, cytokine release syndrome can cause severe lung tissue damage leading to
acute respiratory distress syndrome (ARDS). Here, we address the effects of IFNγ, TNFα, IL …

Acute respiratory distress syndrome (ARDS) is characterized by severe hypoxemia and high-
permeability pulmonary edema. A hallmark of the disease is the presence of lung …

Background. In COVID-19, an uncontrolled inflammatory response might worsen lung
damage, leading to acute respiratory distress syndrome (ARDS). Recent evidence points to …

Disease progression during SARS-CoV-2 infection is tightly linked to the fate of lung
epithelial cells, with severe cases of COVID-19 characterized by direct injury of the alveolar …

Cytokine release syndrome, also called cytokine storm, could cause lung tissue damage,
acute respiratory distress syndrome (ARDS) and even death during SARS-CoV-2 infection …

The mechanisms by which excessive systemic activation of adaptive T lymphocytes, as in
cytokine release syndrome (CRS), leads to innate immune cell-mediated acute lung injury …

Two years after its spreading, the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is still responsible for more than 2000 deaths per day worldwide, despite vaccines …

COVID-19 is a major etiology of acute respiratory distress syndrome (ARDS). The biological
phenotypes and underlying mechanisms in COVID-19-induced ARDS are not fully …

Airway epithelial cells represent the main target of SARS-CoV-2 replication but several
pieces of evidence suggest that endothelial cells (ECs), lining pulmonary blood vessels, are …

Disease progression during SARS-CoV-2 infection is tightly linked to the fate of lung
epithelial cells, with severe cases of COVID-19 characterized by direct injury of the alveolar …