Pathophysiology of migraine: a disorder of sensory processing

PJ Goadsby, PR Holland… - Physiological …, 2017 - journals.physiology.org
Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Current and novel insights into the neurophysiology of migraine and its implications for therapeutics

S Akerman, M Romero-Reyes, PR Holland - Pharmacology & Therapeutics, 2017 - Elsevier
Migraine headache and its associated symptoms have plagued humans for two millennia. It
is manifest throughout the world, and affects more than 1/6 of the global population. It is the …

Pathophysiology of migraine

D Pietrobon, MA Moskowitz - Annual review of physiology, 2013 - annualreviews.org
Migraine is a collection of perplexing neurological conditions in which the brain and its
associated tissues have been implicated as major players during an attack. Once …

New migraine and pain research

R Hargreaves - Headache: The Journal of Head and Face Pain, 2007 - Wiley Online Library
An understanding of the pathophysiology and pharmacology of migraine has been driven by
astute clinical observations, elegant experimental medicine studies and importantly by the …

[HTML][HTML] Migraine pathogenesis and state of pharmacological treatment options

T Sprenger, PJ Goadsby - BMC medicine, 2009 - Springer
Migraine is a largely inherited disorder of the brain characterized by a complex, but
stereotypical, dysfunction of sensory processing. Often the most obvious clinical symptom is …

Neurobiology of migraine

PJ Goadsby, AR Charbit, AP Andreou, S Akerman… - Neuroscience, 2009 - Elsevier
Migraine is a complex disorder of the brain whose mechanisms are only now being
unraveled. It is common, disabling and economically costly. The pain suggests an important …

[HTML][HTML] An update on migraine: current understanding and future directions

F Puledda, R Messina, PJ Goadsby - Journal of neurology, 2017 - Springer
Migraine is a common brain disorder with high disability rates which involves a series of
abnormal neuronal networks, interacting at different levels of the central and peripheral …

Neurobiology of migraine

D Pietrobon, J Striessnig - Nature Reviews Neuroscience, 2003 - nature.com
Migraine—an episodic headache—affects more than 10% of the general population.
Despite recent progress, drug therapy for preventing and treating migraine remains …

Migraine: where and how does the pain originate?

K Messlinger - Experimental brain research, 2009 - Springer
Migraine is a complex neurological disease with a genetic background. Headache is the
most prominent and clinically important symptom of migraine but its origin is still enigmatic …

Migraine: multiple processes, complex pathophysiology

R Burstein, R Noseda, D Borsook - Journal of Neuroscience, 2015 - Soc Neuroscience
Migraine is a common, multifactorial, disabling, recurrent, hereditary neurovascular
headache disorder. It usually strikes sufferers a few times per year in childhood and then …