SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by
the availability of entry receptors on host cells. Here, we show that TMEM106B, a lysosomal …

The interaction of the SARS-CoV-2 spike protein with the cellular receptor ACE2 is believed
to be essential for viral entry into host cells. In a recent paper published in Cell Research, Gu …

Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is broadly accepted that SARS …

Macrophages are key cellular contributors to the pathogenesis of COVID-19, the disease
caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2 …

Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus
has infected more than 46 million people worldwide, killing over one million two hundred …

SARS-CoV-2 entry into host cells is a crucial step for virus tropism, transmission, and
pathogenesis. Angiotensin-converting enzyme 2 (ACE2) has been identified as the primary …

Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), the causative agent
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses angiotensin-
converting enzyme 2 (ACE2) as a binding receptor to enter cells via clathrin-mediated …

Antiviral therapeutics are a front-line defense against virally induced diseases. Because
viruses frequently mutate to escape direct inhibition of viral proteins, there is interest in …