Cigarette smoking combined with genetic variation regulates the m6A methylation of CRNKL1 and is associated with bladder cancer risk

J Yang, Z Ji, F Gao, J Wu, M Du, Z Zhang… - Environmental …, 2024 - Wiley Online Library
Cigarette smoking was known to accelerate the occurrence and development of bladder
cancer by regulating RNA modification. However, the association between the combination …

KCNMB2-AS1 promotes bladder cancer progression through sponging miR-374a-3p to upregulate S100A10

J Zhu, Y Huang, Y Zhang, R Huang, C Huang - Frontiers in Genetics, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) have been reported to play a crucial role in the
pathogenesis of numerous cancers. However, the function of lncRNA KCNMB2-AS1 in …

Anti-cancer effect of LINC00478 in bladder cancer correlates with KDM1A-dependent MMP9 demethylation

HJ Yang, T Liu, Y Xiong - Cell Death Discovery, 2022 - nature.com
Accumulating evidence has highlighted the important roles of long intergenic non-coding
RNAs (lincRNAs) during cancer progression. However, the involvement of LINC00478 in …

An integrative approach for identification of smoking-related genes involving bladder cancer

F Gao, H Li, Z Mao, Y Xiao, M Du, S Wang… - Archives of …, 2023 - Springer
Tobacco smoking is one of the most important environmental risk factors involving bladder
tumorigenesis. However, smoking-related genes in bladder carcinogenesis and …

Transcription factor KLF5 binds a cyclin E1 polymorphic intronic enhancer to confer increased bladder cancer risk

JM Pattison, V Posternak, MD Cole - Molecular Cancer Research, 2016 - AACR
It is well established that environmental toxins, such as exposure to arsenic, are risk factors
in the development of urinary bladder cancer, yet recent genome-wide association studies …

Long non‐coding RNA LINC00673 silencing inhibits proliferation and drug resistance of prostate cancer cells via decreasing KLF4 promoter methylation

Z Jiang, Y Zhang, X Chen, P Wu… - Journal of cellular and …, 2020 - Wiley Online Library
Prostate cancer is one of the major causes of cancer‐related mortality in men across the
world. Recently, long non‐coding RNAs (lncRNAs) and Kruppel‐like factor 4 (KLF4) have …

Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS)

C Faltus, A Lahnsteiner, M Barrdahl, Y Assenov… - International Journal of …, 2022 - mdpi.com
Changes in DNA methylation identified by epigenome-wide association studies (EWAS)
have been recently linked to increased lung cancer risk. However, the cellular effects of …

AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility

Y Xiao, Y Shen, H Song, F Gao, Z Mao, Q Lv, C Qin… - Archives of …, 2024 - Springer
Tobacco carcinogens metabolism-related genes (TCMGs) could generate reactive
metabolites of tobacco carcinogens, which subsequently contributed to multiple diseases …

A genome-wide screen for differentially methylated long noncoding RNAs identified that lncAC007255. 8 is regulated by promoter DNA methylation in Beas-2B cells …

E Chen, J Zhou, E Xu, C Zhang, J Liu, J Zhou, M Li… - Toxicology Letters, 2021 - Elsevier
Tobacco exposure is well known to induce genetic and epigenetic changes that contribute to
the pathogenesis of lung cancer. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a …

LncRNA polymorphisms and urologic cancer risk

E Abdi, S Latifi‐Navid - Environmental and molecular …, 2022 - Wiley Online Library
Urologic cancers involve nearly one‐quarter of all cancers and include the prostate, bladder,
and kidney cancers. Long non‐coding RNAs (LncRNAs) are expressed in a tissue‐specific …