Depression is common, costly, debilitating, and associated with increased risk of suicide. It is
one of the leading global public health problems. Although existing available …

Depression like many diseases is pleiotropic but unlike cancer and Alzheimer's disease for
example, is still largely stigmatized and falls into the dark shadows of human illness. The …

Major depressive disorder is one of the most prevalent mental health disorders. Monoamine-
based antidepressants were the first drugs developed to treat major depressive disorder …

Depression is a leading cause of morbidity and mortality, and its treatment includes a high
percentage of the medications prescribed by physicians. Available antidepressant drugs are …

Background: The World Health Organization (WHO) report has predicted that major
depression will become a key cause of illness-induced disability by the year 2020, second …

Introduction Major depressive disorder is a complex and frequent psychiatric condition that
poses significant challenges to both the patients who experience it and the physicians who …

In this Seminar we discuss developments from the past 5 years in the diagnosis,
neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and …

Major depressive disorder is a remarkably common and often severe psychiatric disorder
associated with high levels of morbidity and mortality. Patients with major depression are …

Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …

The current definition of major depressive disorder (MDD) emerged from efforts to create
reliable diagnostic criteria for clinical and research use. However, despite decades of …