A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs
Z Liu, J Zhou, W Xu, W Deng, Y Wang, M Wang… - Cell research, 2022 - nature.com
The emergence of SARS-CoV-2 variants and potentially other highly pathogenic
sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines. Here, we …
sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines. Here, we …
A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant
Z Liu, JFW Chan, J Zhou, M Wang, Q Wang, G Zhang… - Cell research, 2022 - nature.com
Dear Editor, Since the outbreak of Coronavirus Disease 2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, numerous SARS-CoV-2 …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, numerous SARS-CoV-2 …
A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates
Z Liu, J Zhou, X Wang, W Xu, Z Teng… - Proceedings of the …, 2023 - National Acad Sciences
The recently emerged Omicron subvariants XBB and BQ. 1.1 have presented striking
immune evasion against most monoclonal neutralizing antibodies and convalescent …
immune evasion against most monoclonal neutralizing antibodies and convalescent …
Pan-sarbecovirus neutralizing antibodies in BNT162b2-immunized SARS-CoV-1 survivors
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of
concern pose a challenge to the effectiveness of current vaccines. A vaccine that could …
concern pose a challenge to the effectiveness of current vaccines. A vaccine that could …
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice
Severe acute respiratory syndrome coronaviruses 1 (SARS-CoV) and 2 (SARS-CoV-2),
including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality …
including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality …
SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques
NC Dalvie, LH Tostanoski, SA Rodriguez-Aponte… - Science …, 2022 - science.org
Authorized vaccines against SARS-CoV-2 remain less available in low-and middle-income
countries due to insufficient supply, high costs, and storage requirements. Global immunity …
countries due to insufficient supply, high costs, and storage requirements. Global immunity …
Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease …
of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease …
Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses
Y Wang, M Liu, Y Shen, Y Ma, X Li, Y Zhang, M Liu… - Cell discovery, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
of concern, including Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2) …
of concern, including Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2) …
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine
The rapid emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants that evade immunity elicited by vaccination has placed an imperative on the …
variants that evade immunity elicited by vaccination has placed an imperative on the …
Development of variant‐proof severe acute respiratory syndrome coronavirus 2, pan‐sarbecovirus, and pan‐β‐coronavirus vaccines
J Zhou, Z Liu, G Zhang, W Xu, L Xing… - Journal of Medical …, 2023 - Wiley Online Library
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
variants with high transmission rates and striking immune evasion have posed a serious …
variants with high transmission rates and striking immune evasion have posed a serious …