RNA‐binding proteins in autoimmunity: From genetics to molecular biology

V Lodde, M Floris, E Zoroddu… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Autoimmune diseases (ADs) are chronic pathologies generated by the loss of immune
tolerance to the body's own cells and tissues. There is growing recognition that RNA …

Evolving understandings for the roles of non-coding RNAs in autoimmunity and autoimmune disease

Z Cheng, G Hou, N Shen - Journal of Autoimmunity, 2023 - Elsevier
Autoimmune diseases (ADs) are characterized by aberrant generation of autoreactive
immune cells and persistent inflammation, leading to tissue destruction. Although common …

RNA-binding proteins control gene expression and cell fate in the immune system

M Turner, MD Diaz-Munoz - Nature immunology, 2018 - nature.com
RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …

Post-transcriptional regulation of immune responses by RNA binding proteins

T Mino, O Takeuchi - Proceedings of the Japan Academy, Series B, 2018 - jstage.jst.go.jp
Cytokines are critical mediators of inflammation and host immune defense. Cytokine
production is regulated at both transcriptional and post-transcriptional levels. Post …

[HTML][HTML] Emerging roles for RNA-binding proteins in T lymphocytes

S Monticelli - Immunology letters, 2022 - Elsevier
RNA-binding proteins (RBPs) are essential effectors in defining and regulating gene
expression, and as such their function underlies all cellular processes. Within the immune …

Role of DNA/RNA sensors and contribution to autoimmunity

S Smith, C Jefferies - Cytokine & growth factor reviews, 2014 - Elsevier
Innate immune detection and subsequent immune responses rely on the initial recognition
of pathogen specific molecular motifs. Foreign nucleic acids are key structures recognised …

[HTML][HTML] RBP–RNA interactions in the control of autoimmunity and autoinflammation

J Liu, X Cao - Cell Research, 2023 - nature.com
Autoimmunity and autoinflammation arise from aberrant immunological and inflammatory
responses toward self-components, contributing to various autoimmune diseases and …

[HTML][HTML] Uncovering the role of RNA-binding proteins in gene expression in the immune system

MD Díaz-Muñoz, M Turner - Frontiers in immunology, 2018 - frontiersin.org
Fighting external pathogens requires an ever-changing immune system that relies on tight
regulation of gene expression. Transcriptional control is the first step to build efficient …

Roles of RNA-binding proteins in immune diseases and cancer

S Hashimoto, T Kishimoto - Seminars in cancer biology, 2022 - Elsevier
Genetic information that is transcribed from DNA to mRNA, and then translated from mRNA
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …

RNA-binding proteins in Mendelian disease

A Castello, B Fischer, MW Hentze, T Preiss - Trends in Genetics, 2013 - cell.com
RNA-binding proteins (RBPs) control all aspects of RNA fate, and defects in their function
underlie a broad spectrum of human pathologies. We focus here on two recent studies that …