Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Mesenchymal stem cells (MSC) are adult stem cells with capacity for self-renewal and multi-
lineage differentiation. Initially described in bone marrow, MSC are also present in other …

Cardiovascular disease (CVD) accounts for more deaths globally than any other single
disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) …

Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

Cell based treatments for myocardial infarction have demonstrated efficacy in the laboratory
and in phase I clinical trials, but the understanding of such therapies remains incomplete …

Ischemic heart damage usually triggers cardiomyopathological remodeling and fibrosis, thus
promoting the development of heart functional failure. Mesenchymal stem cells (MSCs) are a …

Experimental and early clinical data suggest that, due to several unique properties,
mesenchymal stem cells (MSCs) may be more effective than other cell types for diseases …

The capacity of stem and progenitor cells to stimulate cardiac regeneration has been studied
for almost 20 years, with very promising preclinical data and mixed clinical results. Several …

Importance of the field: Mesenchymal stem cells (MSCs) have the greatest potential for use
in cell-based therapy of human heart diseases, especially in myocardial infarcts. The …