[HTML][HTML] Inhibition of SARS-CoV-2 Nsp9 ssDNA-Binding Activity and Cytotoxic Effects on H838, H1975, and A549 Human Non-Small Cell Lung Cancer Cells …
HH Su, ES Lin, YH Huang, Y Lien… - International Journal of …, 2024 - mdpi.com
Carnivorous pitcher plants from the genus Nepenthes are renowned for their ethnobotanical
uses. This research explores the therapeutic potential of Nepenthes miranda leaf extract …
uses. This research explores the therapeutic potential of Nepenthes miranda leaf extract …
Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus …
S Kumar, P Kashyap, S Chowdhury, S Kumar… - Phytomedicine, 2021 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) playing havoc across the globe
caused 585,727 deaths and 13,616,593 confirmed cases so far as per World Health …
caused 585,727 deaths and 13,616,593 confirmed cases so far as per World Health …
[HTML][HTML] Exploring the pharmacological aspects of natural phytochemicals against SARS-CoV-2 Nsp14 through an in silico approach
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), possesses an
important bifunctional nonstructural protein (nsp14) with a C-terminal N7-methyltransferase …
important bifunctional nonstructural protein (nsp14) with a C-terminal N7-methyltransferase …
SARS-CoV-2 nsp13 Restricts Episomal DNA Transcription without Affecting Chromosomal DNA
A Li, B Zhang, K Zhao, Z Yin, Y Teng, L Zhang… - Journal of …, 2023 - Am Soc Microbiol
ABSTRACT Nonstructural protein 13 (nsp13), the helicase of SARS-CoV-2, has been shown
to possess multiple functions that are essential for viral replication, and is considered an …
to possess multiple functions that are essential for viral replication, and is considered an …
[HTML][HTML] Senna makki and other active phytochemicals: Myths and realities behind covid19 therapeutic interventions
This study aims to investigate the binding potential of chemical compounds of Senna in
comparison with the experimentally tested active phytochemicals against SARS-CoV-2 …
comparison with the experimentally tested active phytochemicals against SARS-CoV-2 …
[HTML][HTML] Synergistic interactions of repurposed drugs that inhibit Nsp1, a major virulence factor for COVID-19
HT Kao, A Orry, MG Palfreyman, B Porton - Scientific Reports, 2022 - nature.com
Nsp1 is one of the first proteins expressed from the SARS-CoV-2 genome and is a major
virulence factor for COVID-19. A rapid multiplexed assay for detecting the action of Nsp1 …
virulence factor for COVID-19. A rapid multiplexed assay for detecting the action of Nsp1 …
Lysine 164 is critical for SARS-CoV-2 Nsp1 inhibition of host gene expression
Z Shen, G Zhang, Y Yang, M Li… - Journal of General …, 2021 - microbiologyresearch.org
The emerging pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has caused social and economic disruption worldwide, infecting over 9.0 million people and …
has caused social and economic disruption worldwide, infecting over 9.0 million people and …
Potential Drugs Targeting Nsp16 Protein May Corroborates a Promising Approach to Combat SARSCoV-2 Virus
The recent ongoing pandemic caused by SARS-CoV-2 continues to impose devastating
impacts and is accountable for the loss of more than 250,000 human lives within a short …
impacts and is accountable for the loss of more than 250,000 human lives within a short …
[HTML][HTML] Withaniasomnifera phytochemicals possess SARS-CoV-2 RdRp and human TMPRSS2 protein binding potential
KS Prajapati, AK Singh, PP Kushwaha, M Shuaib… - Vegetos, 2023 - Springer
Abstract Coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2) has infected approximately 26 million people and …
syndrome-coronavirus-2 (SARS-CoV-2) has infected approximately 26 million people and …
Virtual screening and molecular dynamics simulation for identification of natural antiviral agents targeting SARS-CoV-2 NSP10
H Zhao, J Liu, L He, L Zhang, R Yu, C Kang - Biochemical and Biophysical …, 2022 - Elsevier
New variations of SARS-CoV-2 continue to emerge in the global pandemic, which may be
resistant to at least some vaccines in COVID-19, indicating that drug and vaccine …
resistant to at least some vaccines in COVID-19, indicating that drug and vaccine …