Mechanical signals are recognized as anabolic to both bone and muscle, but the specific
parameters that are critical to this stimulus remain unknown. Here we examined the potential …

Short durations of extremely small magnitude, high-frequency, mechanical stimuli can
promote anabolic activity in the adult skeleton. Here, it is determined if such signals can …

Bone formation and resorption are sensitive to both external loads arising from gravitational
loading as well to internal loads generated by muscular activity. The question as to which of …

Extremely low-magnitude (0.3 g), high-frequency (30–90 Hz), whole body vibrations can
stimulate bone formation and are hypothesized to provide a surrogate for the oscillations of …

High‐frequency whole body vibrations can be osteogenic, but their efficacy appears limited
to skeletal segments that are weight bearing and thus subject to the induced load. To …

Recent studies suggest that whole-body vibration (WBV) can improve measures of bone
health for certain clinical conditions and ages. In the elderly, there also is particular interest …

There is growing evidence that extremely small mechanical signals, if applied at a
sufficiently high frequency, can serve as anabolic signals to bone tissue. To determine if the …

Low‐amplitude, whole‐body vibration (WBV) may be anabolic for bone. Animal studies of
WBV have not evaluated skeletal effects in aged animals. We exposed 75 male BALB/c mice …

Mechanical loading of the skeleton is necessary to maintain bone structure and strength.
Large amplitude strains associated with vigorous activity typically result in the greatest …

The potential for brief periods of low‐magnitude, high‐frequency mechanical signals to
enhance the musculoskeletal system was evaluated in young women with low BMD. Twelve …