Single dose of a VSV-based vaccine rapidly protects macaques from Marburg virus disease

A Marzi, A Jankeel, AR Menicucci, J Callison… - Frontiers in …, 2021 - frontiersin.org
Marburg virus (MARV) is a member of the filovirus family that causes hemorrhagic disease
with high case fatality rates. MARV is on the priority list of the World Health Organization for …

Protection against marburg virus using a recombinant VSV-vaccine depends on T and B cell activation

A Marzi, AR Menicucci, F Engelmann… - Frontiers in …, 2019 - frontiersin.org
Marburg virus (MARV) is the causative agent of hemorrhagic fever outbreaks with high case
fatality rates. Closely related to Ebola virus, MARV is a filamentous virus with a negative …

Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine

KL O'Donnell, F Feldmann, B Kaza, CS Clancy… - …, 2023 - thelancet.com
Background Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD)
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates

CE Mire, JB Geisbert, KN Agans, BA Satterfield… - PloS one, 2014 - journals.plos.org
The filoviruses, Marburg virus (MARV) and Ebola virus, causes severe hemorrhagic fever
with high mortality in humans and nonhuman primates. A promising filovirus vaccine under …

Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment

KM Daddario-DiCaprio, TW Geisbert, U Ströher… - The Lancet, 2006 - thelancet.com
Background Effective countermeasures are urgently needed to prevent and treat infections
caused by highly pathogenic and biological threat agents such as Marburg virus (MARV) …

Cross-protection against Marburg virus strains by using a live, attenuated recombinant vaccine

KM Daddario-DiCaprio, TW Geisbert… - Journal of …, 2006 - Am Soc Microbiol
Marburg virus (MARV) has been associated with sporadic episodes of hemorrhagic fever,
including a recent highly publicized outbreak in Angola that produced severe disease and …

Immune correlates of postexposure vaccine protection against Marburg virus

C Woolsey, A Jankeel, D Matassov, JB Geisbert… - Scientific reports, 2020 - nature.com
Postexposure immunization can prevent disease and reduce transmission following
pathogen exposure. The rapid immunostimulatory properties of recombinant vesicular …

A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge

C Woolsey, RW Cross, KN Agans… - PLoS neglected …, 2022 - journals.plos.org
Background Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public
health as demonstrated by its high associated mortality rate (23–90%) and recent …

Systematic review of Marburg virus vaccine nonhuman primate studies and human clinical trials

N Dulin, A Spanier, K Merino, JN Hutter, PE Waterman… - Vaccine, 2021 - Elsevier
Background Recent deadly outbreaks of Marburg virus underscore the need for an effective
vaccine. A summary of the latest research is needed for this WHO priority pathogen. This …

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

SM Jones, H Feldmann, U Ströher, JB Geisbert… - Nature medicine, 2005 - nature.com
Vaccines and therapies are urgently needed to address public health needs stemming from
emerging pathogens and biological threat agents such as the filoviruses Ebola virus (EBOV) …