In the three years since the most recent meta-analysis of the association between the
serotonin transported promoter polymorphism (5-HTTLPR), stress and the development of …

Objective: To perform a meta-analysis including all relevant studies exploring the interaction.
Data Sources: We identified studies published through November 2009 in PubMed. Study …

Whereas there is no doubt that the meta-analyses are methodologically sound, it appears
that this technique is only in part suitable for appraising all of the available evidence …

Context Substantial resources are being devoted to identify candidate genes for complex
mental and behavioral disorders through inclusion of environmental exposures following the …

Background Debate is ongoing about what role, if any, variation in the serotonin transporter
linked polymorphic region (5-HTTLPR) plays in depression. Some studies report an …

The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …

Recent meta-analyses have stimulated an active debate on whether the serotonin
transporter gene-linked polymorphic region (5-HTTLPR) is associated with an elevated …

BACKGROUND: Although it is universally accepted that human disease and behavior
depend upon both environmental and genetic variation, a view supported by family and twin …

The question of whether a functional variant in the promoter of the serotonin transporter
gene (5-HTTLPR) influences response to adversity and/or antidepressants has generated …

Objectives A functional polymorphism in the promoter region of the 5-hydroxytryptamine
(serotonin) transporter (5-HTT) gene, termed 5-HTTLPR, alters transcription of the 5-HTT …