Here, we present a physiologically relevant model of the human pulmonary alveoli. This
alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made …

Here we describe a microphysiological system that replicates the functional unit of the living
human lung. This human “breathing lung-on-a-chip” microdevice provides unique …

The air-blood barrier with its complex architecture and dynamic environment is difficult to
mimic in vitro. Lung-on-a-chips enable mimicking the breathing movements using a thin …

Lung‐on‐a‐chip models hold great promise for disease modeling and drug screening.
Herein, inspired by the iridescence phenomenon of soap bubbles, a novel biomimetic 3D …

We report a lung-on-a-chip array that mimics the pulmonary parenchymal environment,
including the thin alveolar barrier and the three-dimensional cyclic strain induced by …

There is an urgent need for physiologically relevant and customizable biochip models of
human lung tissue to provide a niche for lung disease modeling and drug efficacy. Although …

Organs-on-chips have the potential to improve drug development efficiency and decrease
the need for animal testing. For the successful integration of these devices in research and …

With the outbreak of new respiratory viruses and high mortality rates of pulmonary diseases,
physiologically relevant models of human respiratory system are urgently needed to study …

The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the
investigation of complex disease pathomechanisms, are increasingly relying on in vitro lung …

Chronic lung diseases result from alteration and/or destruction of lung tissue, inevitably
causing decreased breathing capacity and quality of life for patients. While animal models …