Objective To determine the clinical effectiveness of implementing early goal-directed therapy
(EGDT) as a routine protocol in the emergency department (ED). Methods Prospective …

BACKGROUND: Early goal-directed therapy (EGDT) has been shown to reduce mortality in
patients with severe sepsis/septic shock, however, implementation of this protocol in the …

Objectives The aim of this study was to determine the outcome of patients with severe sepsis
and septic shock who did and did not receive early goal-directed therapy (EGDT) in the …

Objective Early goal-directed therapy (EGDT) has been shown to decrease mortality in
patients with severe sepsis and septic shock. Consensus guidelines now advocate EGDT for …

Objective: Early goal-directed therapy (EGDT) reduced mortality from septic shock in a
single-center trial. However, implementation of EGDT faces several barriers, including …

Introduction Early structured resuscitation of severe sepsis has been suggested to improve
short term mortality; however, no previous study has examined the long-term effect of this …

Article-at-a-Glance Background The growing number of patients with severe sepsis or septic
shock and the resulting mortality rate (30%) require changes in the current protocols used to …

Background Early goal-directed therapy (EGDT) has been endorsed in the guidelines of the
Surviving Sepsis Campaign as a key strategy to decrease mortality among patients …

Studies and meta-analyses conflict regarding the use of early goal-directed therapy (EGDT)
for septic shock. We sought to clarify the conflict by performing a living systematic review and …

Severe sepsis and septic shock are among the leading causes of mortality in the intensive
care unit. Over a decade ago, early goal-directed therapy (EGDT) emerged as a novel …