Reprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways

K Futosi, S Fodor, A Mócsai - International immunopharmacology, 2013 - Elsevier
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but
their inappropriate activation also contributes to tissue damage during autoimmune and …

Immunoreceptors on neutrophils

DJ van Rees, K Szilagyi, TW Kuijpers, HL Matlung… - Seminars in …, 2016 - Elsevier
Neutrophils play a critical role in the host defense against infection, and they are able to
perform a variety of effector mechanisms for this purpose. However, there are also a number …

Neutrophils in the activation and regulation of innate and adaptive immunity

A Mantovani, MA Cassatella, C Costantini… - Nature reviews …, 2011 - nature.com
Neutrophils have long been viewed as the final effector cells of an acute inflammatory
response, with a primary role in the clearance of extracellular pathogens. However, more …

Neutrophils, host defense, and inflammation: a double‐edged sword

JA Smith - Journal of leukocyte biology, 1994 - Wiley Online Library
Neutrophils play important roles in host defense against all classes of infectious agents but,
paradoxically, they are also involved in the pathology of various inflammatory conditions …

Mechanisms regulating neutrophil responses in immunity, allergy, and autoimmunity

A Özcan, O Boyman - Allergy, 2022 - Wiley Online Library
Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …

Neutrophils cascading their way to inflammation

CD Sadik, ND Kim, AD Luster - Trends in immunology, 2011 - cell.com
Neutrophils are pivotal effector cells of innate immunity. Their recruitment into peripheral
tissues is indispensable for host defense. Given their destructive potential, neutrophil entry …

Regulation of immune responses by neutrophils

J Wang, H Arase - Annals of the New York Academy of …, 2014 - Wiley Online Library
Neutrophils, the most abundant circulating cells in humans, are major pathogen‐killing
immune cells. For many years, these cells were considered to be simple killers at the …

Neutrophil-derived cytokines: facts beyond expression

C Tecchio, A Micheletti, MA Cassatella - Frontiers in immunology, 2014 - frontiersin.org
Polymorphonuclear neutrophils, besides their involvement in primary defense against
infections–mainly through phagocytosis, generation of toxic molecules, release of enzymes …

Neutrophil chemoattractant receptors in health and disease: double-edged swords

M Metzemaekers, M Gouwy, P Proost - Cellular & molecular …, 2020 - nature.com
Neutrophils are frontline cells of the innate immune system. These effector leukocytes are
equipped with intriguing antimicrobial machinery and consequently display high cytotoxic …

The diverse biological functions of neutrophils, beyond the defense against infections

F Yang, C Feng, X Zhang, J Lu, Y Zhao - Inflammation, 2017 - Springer
Polymorphonuclear neutrophils are among the first defense against infection and closely
involved in the initiation of inflammatory response. It is well recognized that this function of …