In Silico Prediction of Andrographolide Dosage Regimens for COVID-19 Treatment
T Saeheng, J Karbwang… - The American Journal of …, 2022 - World Scientific
Andrographolide (APE) has been used for COVID-19 treatment in various clinical settings in
South-East Asia due to its benefits on reduction of viral clearance and prevention of disease …
South-East Asia due to its benefits on reduction of viral clearance and prevention of disease …
The Development of a Physiologically Based Pharmacokinetic (PBPK) Model of Andrographolide in Mice and Scaling it up to Rats, Dogs, and Humans
T Talapphetsakun, J Viyoch, N Waranuch… - Current Drug …, 2022 - ingentaconnect.com
Background: Andrographolide has a potent antiviral effect in the treatment of coronavirus
disease (COVID-19). However, there are no in vivo studies of andrographolide as an anti …
disease (COVID-19). However, there are no in vivo studies of andrographolide as an anti …
[HTML][HTML] A comprehensive review on disposition kinetics and dosage of oral administration of Andrographis paniculata, an alternative herbal medicine, in co-treatment …
P Songvut, T Suriyo, D Panomvana… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a present global health crisis that is driving the
investigation of alternative phytomedicines for antiviral purposes. The evidence suggests …
investigation of alternative phytomedicines for antiviral purposes. The evidence suggests …
Andrographolide Induces anti-SARS-CoV-2 Response Through host-directed Mechanism: an in silico Study
Aim: Considering the present alarming situation of COVID-19 pandemic, we concentrated on
evaluating the efficacy of a novel natural antiviral drug-candidate andrographolide against …
evaluating the efficacy of a novel natural antiviral drug-candidate andrographolide against …
Theoretical basis and effect characteristics of andrographolide against COVID-19
N CAI - Chinese Traditional and Herbal Drugs, 2020 - pesquisa.bvsalud.org
ABSTRACT Since December 2019, coronavirus disease 2019 (COVID-19) has spread
rapidly in China. National Health Commission of the People's Republic of China and local …
rapidly in China. National Health Commission of the People's Republic of China and local …
[PDF][PDF] Identification of Potential Semisynthetic Andrographolide Derivatives to Combat COVID-19 by Targeting the SARS-COV-2 Spike Protein and Human ACE2 …
V Ravichandran - Biointerface Res Appl Chem, 2022 - biointerfaceresearch.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal factor for the
current deadly infectious disease CoVID-19. There is no specific drug available for treating …
current deadly infectious disease CoVID-19. There is no specific drug available for treating …
Andrographolide suppresses SARS-CoV-2 infection by downregulating ACE2 expression: A mechanistic study
Q Li, H Lu, Y Ruan, Y Geng, Z Zhao, Y Liu… - Antiviral …, 2024 - journals.sagepub.com
Angiotensin-converting enzyme 2 (ACE2) is the receptor that enables SARS-CoV-2 to
invade host cells. Previous studies have reported that reducing ACE2 expression may have …
invade host cells. Previous studies have reported that reducing ACE2 expression may have …
Andrographis paniculata (Burm. F.) Wall. Ex Nees, Andrographolide, and Andrographolide Analogues as SARS-CoV-2 Antivirals? A Rapid Review
XY Lim, JSW Chan, TYC Tan, BP Teh… - Natural Product …, 2021 - journals.sagepub.com
Drug repurposing is commonly employed in the search for potential therapeutic agents.
Andrographis paniculata, a medicinal plant commonly used for symptomatic relief of the …
Andrographis paniculata, a medicinal plant commonly used for symptomatic relief of the …
Effect of Andrographis paniculata treatment for patients with early-stage COVID-19 on the prevention of pneumonia: A retrospective cohort study
A Benjaponpitak, T Sawaengtham, T Thaneerat… - medRxiv, 2023 - medrxiv.org
There is a need for safe and cost-effective treatments for COVID-19. Andrographis
paniculata (AP) is an herbal plant that has been used for centuries to treat upper respiratory …
paniculata (AP) is an herbal plant that has been used for centuries to treat upper respiratory …
[HTML][HTML] Andrographis paniculata extract versus placebo in the treatment of COVID-19: a double-blinded randomized control trial
P Kanokkangsadal, C Mingmalairak… - Research in …, 2023 - journals.lww.com
Background and purpose: Andrographis paniculata (Burm. f.) Nees has been recommended
to relieve symptoms and decrease the severity of COVID-19. The clinical study aimed to …
to relieve symptoms and decrease the severity of COVID-19. The clinical study aimed to …