Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder

G Sudre, DE Gildea, GG Shastri, W Sharp, B Jung… - Molecular …, 2023 - nature.com
Despite advances in identifying rare and common genetic variants conferring risk for ADHD,
the lack of a transcriptomic understanding of cortico-striatal brain circuitry has stymied a …

[HTML][HTML] Cortico-striatal differences in the epigenome in attention-deficit/hyperactivity disorder

GG Shastri, G Sudre, K Ahn, B Jung… - Translational …, 2024 - nature.com
While epigenetic modifications have been implicated in ADHD through studies of peripheral
tissue, to date there has been no examination of the epigenome of the brain in the disorder …

Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder

G Poelmans, DL Pauls, JK Buitelaar… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: Attention deficit hyperactivity disorder (ADHD) is a highly heritable
neuropsychiatric disorder. In the present study, the authors investigated the presence of …

Attention-deficit/hyperactivity disorder genomics: update for clinicians

J Elia, J Sackett, T Turner, M Schardt, SC Tang… - Current psychiatry …, 2012 - Springer
Attention deficit, hyperactivity disorder (ADHD) is familial and highly heritable. Several
candidate genes involved in neurotransmission have been identified, however these confer …

[HTML][HTML] Genetic insights into ADHD biology

V Hayman, TV Fernandez - Frontiers in psychiatry, 2018 - frontiersin.org
ADHD is a neurobiological disorder with a large worldwide prevalence causing significant
impairment in children, adolescents, and adults. While there is general agreement about …

The molecular genetic architecture of attention deficit hyperactivity disorder

Z Hawi, TDR Cummins, J Tong, B Johnson, R Lau… - Molecular …, 2015 - nature.com
Attention deficit hyperactivity disorder (ADHD) is a common childhood behavioral condition
which affects 2–10% of school age children worldwide. Although the underlying molecular …

Insights into attention-deficit/hyperactivity disorder from recent genetic studies

I Brikell, C Burton, NR Mota, J Martin - Psychological medicine, 2021 - cambridge.org
Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable
neurodevelopmental disorder (NDD). In this narrative review, we summarize recent …

[HTML][HTML] Transcriptome profiling in adult attention-deficit hyperactivity disorder

N Mortimer, C Sanchez-Mora, P Rovira… - European …, 2020 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with an
estimated heritability of around 70%. Although the largest genome-wide association study …

Advances in the genetics and neurobiology of attention deficit hyperactivity disorder

SV Faraone - Biological Psychiatry, 2006 - biologicalpsychiatryjournal.com
Although the validity of attention deficit hyperactivity disorder (ADHD) as medical disorder
has been widely questioned in the media, the past two decades have produced a wealth of …

[HTML][HTML] Epigenetics and attention-deficit/hyperactivity disorder: new perspectives?

B Mirkovic, A Chagraoui, P Gerardin… - Frontiers in psychiatry, 2020 - frontiersin.org
Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder
with a heavy burden for individuals, families, and society (1). Although ADHD runs within …