Dissecting autism and schizophrenia through neuroimaging genomics

CA Moreau, A Raznahan, P Bellec, M Chakravarty… - Brain, 2021 - academic.oup.com
Neuroimaging genomic studies of autism spectrum disorder and schizophrenia have mainly
adopted a 'top-down'approach, beginning with the behavioural diagnosis, and moving down …

Assessment of neuroanatomical endophenotypes of autism spectrum disorder and association with characteristics of individuals with schizophrenia and the general …

G Hwang, J Wen, S Sotardi, ES Brodkin… - JAMA …, 2023 - jamanetwork.com
Importance Autism spectrum disorder (ASD) is associated with significant clinical,
neuroanatomical, and genetic heterogeneity that limits precision diagnostics and treatment …

[HTML][HTML] Imaging genetics towards a refined diagnosis of schizophrenia

W Jiang, TZ King, JA Turner - Frontiers in psychiatry, 2019 - frontiersin.org
Current diagnoses of schizophrenia and related psychiatric disorders are classified by
phenomenological principles and clinical descriptions while ruling out other symptoms and …

Is schizophrenia on the autism spectrum?

BH King, C Lord - Brain research, 2011 - Elsevier
With the ongoing consideration of the diagnostic criteria for mental disorders that is active in
the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) and International …

Toward neurosubtypes in autism

SJ Hong, JT Vogelstein, A Gozzi, BC Bernhardt… - Biological …, 2020 - Elsevier
There is a consensus that substantial heterogeneity underlies the neurobiology of autism
spectrum disorder (ASD). As such, it has become increasingly clear that a dissection of …

Intermediate or brainless phenotypes for psychiatric research?

A Meyer-Lindenberg - Psychological medicine, 2010 - cambridge.org
For highly heritable brain disorders, such as schizophrenia and autism, investigating genetic
effects on the level of neural systems seems an obvious approach. Nevertheless, the …

Neuroanatomical phenotypes in mental illness: identifying convergent and divergent cortical phenotypes across autism, ADHD and schizophrenia

MTM Park, A Raznahan, P Shaw, N Gogtay… - Journal of Psychiatry and …, 2018 - jpn.ca
Background: There is evidence suggesting neuropsychiatric disorders share genomic,
cognitive and clinical features. Here, we ask if autism-spectrum disorders (ASD), attention …

[HTML][HTML] The neurogenetics of functional connectivity alterations in autism: Insights from subtyping in 657 individuals

J Rasero, A Jimenez-Marin, I Diez, R Toro… - Biological …, 2023 - Elsevier
Background There is little consensus and controversial evidence on anatomical alterations
in the brains of people with autism spectrum disorder (ASD), due in part to the large …

[HTML][HTML] Autistic disorders and schizophrenia: related or remote? An anatomical likelihood estimation

C Cheung, K Yu, G Fung, M Leung, C Wong, Q Li… - PloS one, 2010 - journals.plos.org
Shared genetic and environmental risk factors have been identified for autistic spectrum
disorders (ASD) and schizophrenia. Social interaction, communication, emotion processing …

[HTML][HTML] Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia

CA Moreau, SGW Urchs, K Kuldeep, P Orban… - Nature …, 2020 - nature.com
Abstract 16p11. 2 and 22q11. 2 Copy Number Variants (CNVs) confer high risk for Autism
Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder …