Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites

NL Pereira, N Tosakulwong, CG Scott… - Circulation …, 2015 - Am Heart Assoc
Background—The goal of this study was to identify genetic determinants of plasma N-
terminal proatrial natriuretic peptide (NT-proANP) in the general community by performing a …

Atrial natriuretic peptide gene polymorphisms and risk of ischemic stroke in humans

S Rubattu, R Stanzione, E Di Angelantonio, B Zanda… - Stroke, 2004 - Am Heart Assoc
Background and Purpose—A precise definition of genetic factors responsible for common
forms of stroke is still lacking. The purpose of the present study was to investigate the …

Atrial natriuretic peptide gene G664A polymorphism and the risk of ischemic cerebrovascular disease

A Hassan, N Ali, Y Dong, ND Carter, HS Markus - Neurology, 2001 - AAN Enterprises
The atrial natriuretic peptide (ANP) gene may underlie stroke susceptibility and sensitivity to
cerebral ischemia in an animal model of stroke. The authors investigate its role in humans …

The gene encoding atrial natriuretic peptide and the risk of human stroke

S Rubattu, P Ridker, MJ Stampfer, M Volpe… - Circulation, 1999 - Am Heart Assoc
Background—Recent evidence from an animal model of stroke, the stroke-prone
spontaneously hypertensive rat, implicated the gene encoding atrial natriuretic peptide …

Evaluation of the atrial natriuretic peptide gene in stroke

N Kato, K Ikeda, T Nabika, H Morita, T Sugiyama… - Atherosclerosis, 2002 - Elsevier
The atrial natriuretic peptide (ANP) gene was, though inconclusive, implied to be
etiologically related to stroke in rats and recently in humans. The present study tested the …

Atrial natriuretic peptide (ANP) gene promoter variant and increased susceptibility to early development of hypertension in humans

S Rubattu, A Evangelista, D Barbato, G Barba… - Journal of human …, 2007 - nature.com
Previous evidence supports a role of atrial natriuretic peptide (ANP) as a candidate gene for
hypertension. We characterized an ANP gene promoter variant, which has been associated …

Atrial natriuretic peptide genetic variant rs5065 and risk for cardiovascular disease in the general community: a 9-year follow-up study

V Cannone, BK Huntley, TM Olson, DM Heublein… - …, 2013 - Am Heart Assoc
We analyzed the phenotype associated with the atrial natriuretic peptide (ANP) genetic
variant rs5065 in a random community-based sample. We also assessed and compared the …

Genome-wide association study implicates atrial natriuretic peptide rather than B-type natriuretic peptide in the regulation of blood pressure in the general population

PP Salo, AS Havulinna, T Tukiainen… - Circulation …, 2017 - Am Heart Assoc
Background—Cardiomyocytes secrete atrial natriuretic peptide (ANP) and B-type natriuretic
peptide (BNP) in response to mechanical stretching, making them useful clinical biomarkers …

Genetic analysis of the atrial natriuretic peptide gene in essential hypertension

N KATO, T SUGIYAMA, H MORITA, T NABIKA… - Clinical …, 2000 - portlandpress.com
Atrial natriuretic peptide (ANP) plays an important role in the regulation of blood pressure
through sodium–water homoeostasis. Accordingly, several investigators have raised the …

Association between an atrial natriuretic peptide gene polymorphism and normal blood pressure in subjects of African ancestry: cardiovascular topics

BN Nkeh, AD Tiago, GP Candy… - … Journal of South …, 2002 - journals.co.za
Aim. The roles of the atrial natriuretic peptide (ANP) gene and the clearance receptor of the
ANP (NPRC) gene in hypertensive groups of African ancestry are unclear. The aim of the …