Barriers and shortcomings in access to cardiovascular management and prevention for familial hypercholesterolemia during the COVID‐19 pandemic

H Huang, KSK Leung, T Garg, A Mazzoleni… - Clinical …, 2023 - Wiley Online Library
Familial hypercholesterolemia (FH) is a hereditary condition caused by mutations in the lipid
pathway. The goal in managing FH is to reduce circulating low‐density lipoprotein …

Familial hypercholesterolaemia and COVID-19: a two-hit scenario for endothelial dysfunction amenable to treatment

A Vuorio, F Raal, M Kaste, PT Kovanen - Atherosclerosis, 2021 - Elsevier
Patients with familial hypercholesterolemia (FH) are likely at increased risk for COVID-19
complications in the acute phase of the infection, and for a long time thereafter. Because in …

Prevention of cardiovascular burden in COVID-19 patients suffering from familial hypercholesterolemia: a global challenge

A Vuorio, PT Kovanen, RD Santos, F Raal - Cardiology and therapy, 2022 - Springer
A recent meta-analysis of over 20,000 individuals showed that hospitalized COVID-19
patients with acute myocardial injury had more than fourfold higher mortality than those …

Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic

M Banach, PE Penson, Z Fras, M Vrablik, D Pella… - Pharmacological …, 2020 - Elsevier
Abstract Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of
cardiovascular disease, which is associated with poor outcomes from coronavirus infections …

[HTML][HTML] Patients with familial hypercholesterolemia and COVID-19: efficient and ongoing cholesterol lowering is paramount for the prevention of acute myocardial …

PT Kovanen, F Raal, A Vuorio - American Journal of Preventive …, 2021 - ncbi.nlm.nih.gov
We respectfully submit this letter in response to the May 2021 article “COVID-19 associated
risks of myocardial infarction in persons with familial hypercholesterolemia with or without …

Negative impact of COVID-19 pandemic on the lifestyle and management of patients with homozygous familial hypercholesterolemia

M Kayikcioglu, L Tokgozoglu, OK Tuncel… - Journal of clinical …, 2020 - lipidjournal.com
The sudden outbreak of coronavirus disease 2019 (COVID-19) caused unprecedented
pressure on the community and the national health systems. 1, 2 The irrepressible …

[PDF][PDF] Prevention of endothelial dysfunction and thrombotic events in COVID-19 patients with familial hypercholesterolemia

A Vuorio, PT Kovanen - J Clin Lipidol, 2020 - helda.helsinki.fi
The importance of dyslipidemia medications in patients with coronavirus disease 2019
(COVID-19) is currently not sufficiently recognized in the prevention of thrombotic events. 1 …

[HTML][HTML] Familial Hypercholesterolemia Patients with COVID-19—Effective Cholesterol-Lowering Therapy is Urgent both during and after Infection

A Vuorio, F Raal, PT Kovanen - Reviews in Cardiovascular Medicine, 2022 - imrpress.com
Heterozygous familial hypercholesterolemia (HeFH) patients are the prime example of
subjects who are at high risk for both acute myocardial infarction (AMI) and ischemic stroke …

[HTML][HTML] COVID-19 associated risks of myocardial infarction in persons with familial hypercholesterolemia with or without ASCVD

KD Myers, K Wilemon, MP McGowan… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD), hypertension, and heart failure are associated with higher
rates of coronavirus disease 2019 (COVID-19) related morbidity and mortality [1, 2] …

Direct and indirect effects of SARS-CoV-2 pandemic in subjects with familial hypercholesterolemia: a single lipid-center real-world evaluation

R Scicali, S Piro, V Ferrara, S Di Mauro… - Journal of Clinical …, 2021 - mdpi.com
We evaluated the impact of direct and indirect effects of SARS-CoV-2 infection in subjects
with familial hypercholesterolemia (FH). In this observational, retrospective study, 260 FH …