Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer

L Colucci-D'Amato, L Speranza, F Volpicelli - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

The role of brain derived neurotrophic factor in central nervous system

Y Li, F Li, D Qin, H Chen, J Wang, J Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Cellular and molecular mechanisms of the brain-derived neurotrophic factor in physiological and pathological conditions

V Begni, MA Riva, A Cattaneo - Clinical Science, 2017 - portlandpress.com
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the
central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection …

[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Actions of brain-derived neurotrophin factor in the neurogenesis and neuronal function, and its involvement in the pathophysiology of brain diseases

T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2018 - mdpi.com
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …

BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity

P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …

Brain-derived neurotrophic factor as a drug target for CNS disorders

S Pezet, M Malcangio - Expert opinion on therapeutic targets, 2004 - Taylor & Francis
Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family of trophic
factors. BDNF is widely and abundantly expressed in the CNS and is available to some …

Brain-derived neurotrophic factor: a novel dynamically regulated therapeutic modulator in neurological disorders

V Sharma, TG Singh, A Kaur, A Mannan… - Neurochemical …, 2023 - Springer
The growth factor brain-derived neurotrophic factor (BDNF), and its receptor tropomyosin-
related kinase receptor type B (TrkB) play an active role in numerous areas of the adult …

[HTML][HTML] Functional interactions between steroid hormones and neurotrophin BDNF

T Numakawa, D Yokomaku, M Richards… - World Journal of …, 2010 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF), a critical neurotrophin, regulates many neuronal
aspects including cell differentiation, cell survival, neurotransmission, and synaptic plasticity …

BDNF and memory processing

P Bekinschtein, M Cammarota, JH Medina - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor has emerged as one of the most important molecules
involved in memory. Its wide role in different types of memories that depend on different …