Eye tracking dysfunction in schizophrenia: characterization and pathophysiology

DL Levy, AB Sereno, DC Gooding… - … of schizophrenia and its …, 2010 - Springer
Eye tracking dysfunction (ETD) is one of the most widely replicated behavioral deficits in
schizophrenia and is over-represented in clinically unaffected first-degree relatives of …

Eye tracking abnormalities in schizophrenia: evidence for dysfunction in the frontal eye fields

JA Sweeney, B Luna, NM Srinivasagam… - Biological …, 1998 - Elsevier
Background: Eye tracking deficits are robust abnormalities in schizophrenia, but the
neurobiological disturbance underlying these deficits is not known. Methods: To clarify the …

Pursuit tracking impairments in schizophrenia and mood disorders: step-ramp studies with unmedicated patients

JA Sweeney, B Luna, GL Haas, MS Keshavan… - Biological …, 1999 - Elsevier
Background: Eye tracking abnormalities are highly prevalent in schizophrenia, and are
among the most promising phenotypic familial markers for the disorder. The …

Quantitative characterization of eye tracking dysfunction in schizophrenia

DL Levy, CM Lajonchere, B Dorogusker, DK Min… - Schizophrenia …, 2000 - Elsevier
The purpose of this study was to characterize the nature of the processes that are involved in
eye tracking dysfunction (ETD). We identified a combination of quantitative measures that …

Eye-tracking dysfunction (ETD) in families with sporadic and familial schizophrenia

R Lencer, CP Malchow, K Trillenberg-Krecker… - Biological …, 2000 - Elsevier
Background: Within the field of genetic schizophrenia research, eye-tracking dysfunction can
be regarded as a putative trait marker in families with multiple occurrences of the disease …

Refining the predictive pursuit endophenotype in schizophrenia

LE Hong, KA Turano, H O'Neill, L Hao, I Wonodi… - Biological …, 2008 - Elsevier
BACKGROUND: To utilize fully a schizophrenia endophenotype in gene search and
subsequent neurobiological studies, it is critical that the precise underlying physiologic …

Eye movement dysfunction in first-degree relatives of patients with schizophrenia: a meta-analytic evaluation of candidate endophenotypes

ME Calkins, WG Iacono, DS Ones - Brain and cognition, 2008 - Elsevier
Several forms of eye movement dysfunction (EMD) are regarded as promising candidate
endophenotypes of schizophrenia. Discrepancies in individual study results have led to …

Eye movements and the search for the essence of schizophrenia

PS Holzman - Brain research reviews, 2000 - Elsevier
Clinical Schizophrenia has eluded precise description because of its protean phenotypic
manifestations and variable clinical course, a variability that also makes it difficult to discover …

Specific motion processing pathway deficit during eye tracking in schizophrenia: a performance-matched functional magnetic resonance imaging study

LE Hong, M Tagamets, M Avila, I Wonodi, H Holcomb… - Biological …, 2005 - Elsevier
BACKGROUND: The neural mechanisms underlying smooth pursuit eye movement (SPEM)
abnormalities in schizophrenia are not well understood. Previous evidence suggests that a …

Eye tracking and schizophrenia: a selective review

DL Levy, PS Holzman, S Matthysse… - Schizophrenia …, 1994 - academic.oup.com
The replications of the finding of eye tracking dysfunction (ETD) in schizophrenia patients
and their first-degree relatives suggest that ETD may be informative in studies of a …