The bone matrix plays an indispensable role in the human body, and its unique
biomechanical and mechanobiological properties have received much attention. The bone …

Bone is a mechano-responsive tissue that adapts to changes in its mechanical environment.
Increases in strain lead to increased bone mass acquisition, whereas decreases in strain …

Publisher Summary This chapter focuses on the biomechanical properties of bones. Bone is
a physiologically dynamic tissue whose primary functions are to provide a mechanical …

While it has been long appreciated that biomechanical forces are involved in bone
remodeling and repair, the actual mechanism by which a physical force is translated to the …

Osteocytes are believed to be the mechanical sensor cells in bone. One potential physical
mechanism for the mechanosensing process is that osteocytes directly sense the …

In order to obtain bones that combine a proper resistance against mechanical failure with a
minimum use of material, bone mass and its architecture are continuously being adapted to …

The skeleton's primary mechanical function is to provide rigid levers for muscles to act
against as they hold the body upright in defiance of gravity. Many bones are exposed to …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Bones with complicated hierarchical configuration and microstructures constitute the load-
bearing system. Mechanical loading plays an essential role in maintaining bone health and …

In 1892, JL Wolff proposed that bone could respond to mechanical and biophysical stimuli
as a dynamic organ. This theory presents a unique opportunity for investigations on bone …