[HTML][HTML] Phage Therapy for Cardiac Implantable Electronic Devices and Vascular Grafts: A Targeted Literature Review

M Passerini, F Petri, GA Suh - Pathogens, 2024 - mdpi.com
Infections of cardiac implantable electronic devices (CIEDs) and vascular grafts are some of
the most dreaded complications of these otherwise life-saving devices. Many of these …

[HTML][HTML] Bacteriophages for the treatment of graft infections in cardiovascular medicine

S Junghans, SV Rojas, R Skusa, A Püschel… - Antibiotics, 2021 - mdpi.com
Bacterial infections of vascular grafts represent a major burden in cardiovascular medicine,
which is related to an increase in morbidity and mortality. Different factors that are …

[HTML][HTML] The Safety and Efficacy of Phage Therapy for Infections in Cardiac and Peripheral Vascular Surgery: A Systematic Review

EA Simpson, CS MacLeod, HJ Stacey, J Nagy… - Antibiotics, 2023 - mdpi.com
New approaches to managing infections in cardiac and peripheral vascular surgery are
required to reduce costs to patients and healthcare providers. Bacteriophage (phage) …

Pseudomonas aeruginosa ventricular assist device infections: findings from ineffective phage therapies in five cases

S Aslam, D Roach, MP Nikolich, B Biswas… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Left ventricular assist devices (LVAD) are increasingly used for management of heart failure;
infection remains a frequent complication. Phage therapy has been successful in a variety of …

Successful bacteriophage treatment of infection involving cardiac implantable electronic device and aortic graft: a Trojan horse concept

V Exarchos, T Tkhilaishvili, E Potapov, C Starck… - EP …, 2020 - academic.oup.com
We discuss the case of a 41-year-old man with a right-sided pocket infection and a history of
extensive aortic surgery as well as a right carotid subclavian bypass in the presence of …

Bacteriophage therapy as a treatment option for complex cardiovascular implant infection: The German Heart Center Berlin experience

T Tkhilaishvili, E Potapov, C Starck, J Mulzer… - The Journal of Heart and …, 2022 - Elsevier
Conventional antimicrobials have low or no activity against multidrug-resistant or chronic
implant-associated infections. Lytic bacteriophages can rapidly and selectively kill bacteria …

Phage Therapy for Limb-threatening Prosthetic Knee Klebsiella pneumoniae Infection: Case Report and In Vitro Characterization of Anti-biofilm Activity

EJ Cano, KM Caflisch, PL Bollyky… - Clinical Infectious …, 2021 - academic.oup.com
Background Prosthetic joint infection (PJI) is a potentially limb-threatening complication of
total knee arthroplasty. Phage therapy is a promising strategy to manage such infections …

[HTML][HTML] Bacteriophage-enriched galenic for intrapericardial ventricular assist device infection

SV Rojas, S Junghans, H Fox, K Lazouski, R Schramm… - Antibiotics, 2022 - mdpi.com
We report a case of severe outflow graft infection following left ventricular assist device
(LVAD) implantation. A 51-year old male LVAD patient was readmitted to our hospital …

[HTML][HTML] Phage therapy, a salvage treatment for multidrug-resistant bacteria causing infective endocarditis

HF Hetta, ZI Rashed, YN Ramadan, IMS Al-Kadmy… - Biomedicines, 2023 - mdpi.com
Infective endocarditis (IE) is defined as an infection of the endocardium, or inner surface of
the heart, most frequently affecting the heart valves or implanted cardiac devices. Despite its …

Phage therapy in orthopaedic implant-associated infections

P Rogóż, DF Amanatullah, R Międzybrodzki… - Phage therapy: a …, 2019 - Springer
Implant-associated infection (IAI) remains a significant issue in orthopaedic surgery.
Bacteriophages are naturally occurring viruses that kill bacteria. Bacteriophages are being …