Immunopathogenesis of viral infections in neurological autoimmune disease

MA Habibi, F Nezhad Shamohammadi, T Rajaei… - BMC neurology, 2023 - Springer
Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-
antigens. Several factors play a role in inducing autoimmunity, including genetic and …

Viruses can silently prime for and trigger central nervous system autoimmune disease

DJ Theil, I Tsunoda, F Rodriguez, JL Whitton… - Journal of …, 2001 - Springer
Although many viruses have been isolated from patients with multiple sclerosis (MS), as yet,
no one agent has been demonstrated to cause MS. In contrast, epidemiological data …

Can virus infections trigger autoimmune disease?

RS Fujinami - Journal of autoimmunity, 2001 - Elsevier
This review will examine various infectious parameters that could lead to enhancement or
exacerbation of autoimmune disease. Multiple sclerosis (MS) will be the prototype human …

Post-infectious neurological disorders

KM Blackburn, C Wang - Therapeutic advances in …, 2020 - journals.sagepub.com
A multitude of environmental factors can result in breakdown of immune tolerance in
susceptible hosts. Infectious pathogens are among the most important environmental …

Virus-mediated autoimmunity in multiple sclerosis

N Grigoriadis, GM Hadjigeorgiou - Journal of autoimmune diseases, 2006 - Springer
Epidemiological data suggest the notion that in Multiple Sclerosis (MS) is an acquired
autoimmune disease and the cause may be an environmental factor (s), probably infectious …

Virus-induced autoimmune reactions in the CNS

PJ Talbot, D Arnold, JP Antel - The Mechanisms of Neuronal Damage in …, 2001 - Springer
Neurologic diseases are diverse and often not well-understood, despite the tremendous
health care problems they pose, such as the estimated 22 million persons worldwide who …

Obstacles to identifying viruses that cause autoimmune disease

MG von Herrath - Journal of Neuroimmunology, 2000 - Elsevier
In addition to a clear genetic disposition, environmental factors and viral infections are
thought to play a role in the pathogenesis of autoimmune diseases such as type I diabetes …

Infection, Immunodeficiency, and inflammatory diseases in autoimmune neurology

AL Piquet, SL Clardy - Seminars in Neurology, 2018 - thieme-connect.com
When patients present with neurological syndromes, such as encephalopathy/encephalitis,
meningitis, and/or myelopathy/myelitis, the differential diagnosis is often broad, including …

Autoimmunity as the body's defense mechanism against the enemy within: Development of therapeutic vaccines for neurodegenerative disorders

M Schwartz - Journal of neurovirology, 2002 - Springer
Insults to the central nervous system (CNS), whether of microbial or microbe-free origin,
result in tissue damage. Until recently, it was generally believed that only microbe-related …

Intrathecal antibody production against epstein-barr, herpes simplex, and other neurotropic viruses in autoimmune encephalitis

P Schwenkenbecher, T Skripuletz… - Neurology …, 2021 - AAN Enterprises
Background and Objectives Neurotropic viruses are suspected to play a role in the
pathogenesis of autoimmune diseases of the CNS such as the association between the …