T helper type (Th1/Th2) responses to SARS-CoV-2 and influenza A (H1N1) virus: From cytokines produced to immune responses

E Aleebrahim-Dehkordi, B Molavi, M Mokhtari… - Transplant …, 2022 - Elsevier
Cytokines produced by T helper cells (T h cells) have essential roles in the body's defense
against viruses. Type 1 T helper (Th1) cells are essential for the host defense toward …

[HTML][HTML] T cell response to SARS-CoV-2 infection in humans: A systematic review

M Shrotri, MCI van Schalkwyk, N Post, D Eddy… - PloS one, 2021 - journals.plos.org
Background Understanding the T cell response to SARS-CoV-2 is critical to vaccine
development, epidemiological surveillance and disease control strategies. This systematic …

[HTML][HTML] COVID-19 and the immune system

J Paces, Z Strizova, S Daniel, J Cerny - Physiological research, 2020 - ncbi.nlm.nih.gov
A close interaction between the virus SARS-CoV-2 and the immune system of an individual
results in a diverse clinical manifestation of the COVID-19 disease. While adaptive immune …

[HTML][HTML] Updated insights into the T cell-mediated immune response against SARS-CoV-2: a step towards efficient and reliable vaccines

M Dhawan, AA Rabaan, MMA Fawarah, SA Almuthree… - Vaccines, 2023 - mdpi.com
The emergence of novel variants of SARS-CoV-2 and their abilities to evade the immune
response elicited through presently available vaccination makes it essential to recognize the …

[HTML][HTML] Peculiarities of the T cell immune response in COVID-19

D Kudlay, I Kofiadi, M Khaitov - Vaccines, 2022 - mdpi.com
Understanding the T cell response to SARS-CoV-2 is critical to vaccine development,
epidemiological surveillance, and control strategies for this disease. This review provides …

T cell immunobiology and cytokine storm of COVID‐19

XH Luo, Y Zhu, J Mao, RC Du - Scandinavian journal of …, 2021 - Wiley Online Library
Abstract 2019 coronavirus disease (COVID‐19) presents as a newly recognized pneumonia
and could rapidly progress into acute respiratory distress syndrome which has brought …

[HTML][HTML] Overview of immune response during SARS-CoV-2 infection: lessons from the past

VK Shah, P Firmal, A Alam, D Ganguly… - Frontiers in …, 2020 - frontiersin.org
After the 1918 flu pandemic, the world is again facing a similar situation. However, the
advancement in medical science has made it possible to identify that the novel infectious …

Dynamic changes of lymphocyte subsets in the course of COVID-19

M Rezaei, M Marjani, S Mahmoudi, E Mortaz… - … Archives of Allergy and …, 2021 - karger.com
Background: Although the pathophysiology of coronavirus disease 2019 (COVID-19) is not
clearly defined, among the proposed mechanisms, immune system dysfunction is more …

[HTML][HTML] Immune characteristics of severe and critical COVID-19 patients

L Yang, J Gou, J Gao, L Huang, Z Zhu, S Ji… - Signal transduction and …, 2020 - nature.com
Recently, the novel coronavirus disease (COVID-19) has broken out worldwide, 1 with rapid
increase of infected patients. COVID-19 dominantly leads to pneumonia. 2 Among these …

[HTML][HTML] An early Th1 response is a key factor for a favorable COVID-19 evolution

FJ Gil-Etayo, S Garcinuño, A Utrero-Rico… - Biomedicines, 2022 - mdpi.com
The Th1/Th2 balance plays a crucial role in the progression of different pathologies and is a
determining factor in the evolution of infectious diseases. This work has aimed to evaluate …